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(7S)-3',4',6,8-Tetrahydro-7'-methoxy-2'-methyl-6-methylenespiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol

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(7S)-3',4',6,8-Tetrahydro-7'-methoxy-2'-methyl-6-methylenespiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol Basic information
Product Name:(7S)-3',4',6,8-Tetrahydro-7'-methoxy-2'-methyl-6-methylenespiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol
Synonyms:(7S)-3',4',6,8-Tetrahydro-7'-methoxy-2'-methyl-6-methylenespiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol;Ochotensine;Spiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol, 3',4',6,8-tetrahydro-7'-methoxy-2'-methyl-6-methylene-, (7'S)-
CAS:4959-88-0
MF:C21H21NO4
MW:351.4
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Mol File:4959-88-0.mol
(7S)-3',4',6,8-Tetrahydro-7'-methoxy-2'-methyl-6-methylenespiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol Structure
(7S)-3',4',6,8-Tetrahydro-7'-methoxy-2'-methyl-6-methylenespiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol Chemical Properties
Melting point 252°C
Boiling point 500.0±50.0 °C(Predicted)
density 1.37±0.1 g/cm3(Predicted)
pka10.48±0.20(Predicted)
Safety Information
MSDS Information
(7S)-3',4',6,8-Tetrahydro-7'-methoxy-2'-methyl-6-methylenespiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol Usage And Synthesis
DescriptionThis phenolic alkaloid occurs in Corydalis ochotensis and C. sibirica Pers. It is dextrorotatory with [Q:l~4 + 51.7° (CHCI3) and [o:J~3 + 63.9° (0.1 N/HCI). The methiodide yields tetragonal crystals from MeOH with m.p. 215°C. The 0- methyl ether is ochotensimine (q.v.). The above structure has been confirmed by the total synthesis of the optically inactive form of the alkaloid.
DefinitionChEBI: Ochotensine is a member of isoquinolines.
ReferencesManske., Can. J. Res., 18B, 75 (1940)
McLean, Mei-Sie Lin, McDonald, Trotter., Tetrahedron Lett., 185 (1966)
McDonald, Trotter., J. Chern. Soc., B, 929 (1966)
Total synthesis: Irie, Kishimoto, Uyeo., J. Chern. Soc., C, 3051 (1968)
(7S)-3',4',6,8-Tetrahydro-7'-methoxy-2'-methyl-6-methylenespiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol Preparation Products And Raw materials
Tag:(7S)-3',4',6,8-Tetrahydro-7'-methoxy-2'-methyl-6-methylenespiro[7H-indeno[4,5-d]-1,3-dioxole-7,1'(2'H)-isoquinolin]-6'-ol(4959-88-0) Related Product Information