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| | 3-benzyl-6-bromo-2-chloroquinoline Basic information |
| Product Name: | 3-benzyl-6-bromo-2-chloroquinoline | | Synonyms: | 3-benzyl-6-bromo-2-chloroquinoline;6-Bromo-2-chloro-3-(phenylmethyl)quinoline;Bedaquiline Impurity B;Quinoline, 6-bromo-2-chloro-3-(phenylmethyl)-;Bedaquiline Fumarate Impurity 5;Brilanestrant Impurity 11;3-benzyl-6-bromo-2-chloroquinoline（Beida quinoline intermediate ）;6-Bromo-3-benzyl-2-chloroquinolone | | CAS: | 654655-68-2 | | MF: | C16H11BrClN | | MW: | 332.62 | | EINECS: | | | Product Categories: | bedaquiline intermediates | | Mol File: | 654655-68-2.mol |  |
| | 3-benzyl-6-bromo-2-chloroquinoline Chemical Properties |
| Melting point | 111-112℃ | | Boiling point | 435.9±40.0 °C(Predicted) | | density | 1.482±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | pka | -0.42±0.50(Predicted) |
| | 3-benzyl-6-bromo-2-chloroquinoline Usage And Synthesis |
| Uses | 3-Benzyl-6-bromo-2-chloroquinoline is an intermediate in the synthesis of (αS,βR)-Bedaquiline (B119540), which is a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis. |
| | 3-benzyl-6-bromo-2-chloroquinoline Preparation Products And Raw materials |
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