二氢若丹明123
| 中文名称 | 二氢若丹明123 |
|---|---|
| 中文同义词 | 二氢罗丹明;二氢若丹明123;二氢罗丹明123;二氢罗丹明123(5 MM DMSO溶液)DIHYDRORHODAMINE 123 *5 MM SOLUTION IN DMSO;二氢罗丹明123(5 MM DMSO溶液);二氢罗丹明 123 *真空包装*;活性氧 二氢罗丹明 123;2-(3,6-二氨基-9H-黄嘌呤-9-基)-苯甲酸甲酯 |
| 英文名称 | DIHYDRORHODAMINE 123 |
| 英文同义词 | DIHYDRORHODAMINE 123;DHR;DHR123;2-(3,6-DIAMINO-9H-XANTHEN-9-YL)-BENZOIC ACID, METHYL ESTER;Dihydrohodamine 123;Dihydrorhodamine;DIHYDRORHODAMINE 123, FOR FLUOR-ESCENCE;Dihydrorhodamine123(DHR123) |
| CAS号 | 109244-58-8 |
| 分子式 | C21H18N2O3 |
| 分子量 | 346.38 |
| EINECS号 | |
| 相关类别 | 生物活性小分子;荧光探针，标记，颗粒和染色;细胞生物学;分析试剂-显色剂;生化试剂;对照品;Xanthene;AlphabeticalStains and Dyes;DFluorescent Probes, Labels, Particles and Stains;Fluorescent Enzyme Substrates;Fluorescent Enzyme Substrates for Flow Cytometry;Fluorescent Probes, Labels, Particles and Stains;Stains&Dyes, A to |
| Mol文件 | 109244-58-8.mol |
| 结构式 |  |
二氢若丹明123 性质
| 熔点 | 163–165℃ |
|---|---|
| 沸点 | 526.9±50.0 °C(Predicted) |
| 密度 | 1.313±0.06 g/cm3(Predicted) |
| 储存条件 | -20°C |
| 溶解度 | 二甲基亚砜：>5mg/mL |
| 形态 | 粉末 |
| 酸度系数(pKa) | 4.70 ± 0.40, most basic, temperature: 25 °C |
| 颜色 | 浅红色或粉白色 |
| 最大波长(λmax) | 289 nm |
| BRN | 5989965 |
| 生物领域应用 | Generating,detecting & measuring reactive oxygen species; generating,detecting & measuring reactive nitrogen species; detecting phosphates,peroxynitrile; measuring respiratory burst; chronic granulomatous disease DHR assay; screening |
Dihydrorhodamine 123 (DHR 123) 是一种荧光探针 (λex=488 nm，λem=525 nm)。
In the presence of 10 μM Dihydrorhodamine 123 (DHR 123) the stimulation of the neutrophil NADPH oxidase by the addition of 50 nM phorbol 12-myristate 13-acetat (PMA) resultes in an increase in the rate of rhodamine generation. The fluorescent intensity of the cells, in the presence of 10 μM Dihydrorhodamine 123, increases with time following the addition of 50 nM PMA. In the presence of 10 μM Dihydrorhodamine 123, induced HL60 cells show a sustained increase in fluorescence following the addition of 50 nM PMA.
用途
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