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| | PF-5190457 Basic information |
| Product Name: | PF-5190457 | | Synonyms: | PF-5190457;1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone;PF-05190457 >=95% (HPLC);PF-05190457;PF 5190457,Growth hormone secretagogue receptor,PF 05190457,PF-5190457,PF5190457,GHSR,Inhibitor,PF05190457,inhibit;Ethanone, 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-;(R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethanone | | CAS: | 1334782-79-4 | | MF: | C29H32N6OS | | MW: | 512.67 | | EINECS: | | | Product Categories: | | | Mol File: | 1334782-79-4.mol |  |
| | PF-5190457 Chemical Properties |
| density | 1.41±0.1 g/cm3(Predicted) | | storage temp. | room temp | | solubility | DMSO: 250 mg/mL (487.64 mM) | | form | powder | | pka | 8.38±0.20(Predicted) | | color | white to beige | | optical activity | [α]/D +45 to +55°, c = 0.5 in methanol |
| | PF-5190457 Usage And Synthesis |
| Uses | PF 5190457 is a potent, selective, and orally bioavailable ghrelin receptor inverse agonist. | | Biochem/physiol Actions | PF-05190457 is an orally available, potent and selective ghrelin receptor inverse agonist. PF-05190457 potently increases insulin secretion in glucose-stimulated human islets. | | storage | Store at -20°C |
| | PF-5190457 Preparation Products And Raw materials |
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