| Company Name: |
Adamas Reagent, Ltd.
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| Tel: |
400-6009262 16621234537 |
| Email: |
zhangsn@titansci.com |
| Products Intro: |
Product Name:Dacomitinib Impurity 5
CAS:2190490-31-2
Purity:对照品 Package:10mg~500mg Remarks:AC000527005
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| Company Name: |
Shanghai Kewel Chemical Co., Ltd.
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| Tel: |
021-64609169 18901607656 |
| Email: |
greensnown@163.com |
| Products Intro: |
Product Name:Dacomitinib Impurity 3
CAS:2190490-31-2
Purity:95+ HPLC; Package:10mg;25mg;50mg;100mg
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| | Dacomitinib Impurity WYH Basic information |
| Product Name: | Dacomitinib Impurity WYH | | Synonyms: | Dacomitinib Impurity WYH;Dacomitinib Impurity 3;2-Pyrrolidinone, 1-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-5-hydroxy-;Des-(4-(1-piperidinyl)-2-Butenamide) Dacomitinib-5-hydroxypyrrolidin-2-one;1-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one (Dacomitinib Impurity);1-(4-((3-Chloro-4-fluorocyclohexyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one;Dacotinib impurity 2 | | CAS: | 2190490-31-2 | | MF: | C19H16ClFN4O3 | | MW: | 402.81 | | EINECS: | | | Product Categories: | | | Mol File: | 2190490-31-2.mol |  |
| | Dacomitinib Impurity WYH Chemical Properties |
| Boiling point | 662.5±55.0 °C(Predicted) | | density | 1.524±0.06 g/cm3(Predicted) | | pka | 12.39±0.20(Predicted) |
| | Dacomitinib Impurity WYH Usage And Synthesis |
| Uses | Des-(4-(1-piperidinyl)-2-Butenamide) Dacomitinib-5-hydroxypyrrolidin-2-one is a derivative of Dacomitinib (D101575), which is an Erb-inhibitor, or an inhibitor of the members of the epidermal growth factor receptor family. Used as an ant-cancer agent due to observation of over-expressed epidermal growth factor receptor in nearly all cases of squamous cell carcinoma in the head and neck. |
| | Dacomitinib Impurity WYH Preparation Products And Raw materials |
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