| Company Name: |
Affinity（Wuhan）Ltd. Gold
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| Tel: |
15841022315 |
| Email: |
sales@affinitytech.cn |
| Products Intro: |
Product Name:BCN-PEG3-VC-PFP Ester
CAS:2353409-45-5
Purity:>96% Package:100mg;1g;10g
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BCN-PEG3-VC-PFP ester manufacturers
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| | BCN-PEG3-VC-PFP ester Basic information |
| Product Name: | BCN-PEG3-VC-PFP ester | | Synonyms: | BCN-PEG3-VC-PFP ester;endo BCN-PEG3-VC-PFP Ester;L-Ornithine, N-[16-(1R,8S)-bicyclo[6.1.0]non-4-yn-9-yl-1,14-dioxo-4,7,10,15-tetraoxa-13-azahexadec-1-yl]-L-valyl-N5-(aminocarbonyl)-, 2,3,4,5,6-pentafluorophenyl ester | | CAS: | 2353409-45-5 | | MF: | C37H50F5N5O10 | | MW: | 819.81 | | EINECS: | | | Product Categories: | | | Mol File: | 2353409-45-5.mol |  |
| | BCN-PEG3-VC-PFP ester Chemical Properties |
| Boiling point | 925.6±65.0 °C(Predicted) | | density | 1.34±0.1 g/cm3(Predicted) | | solubility | Soluble in DMSO, DCM, DMF | | pka | 12.05±0.46(Predicted) |
| | BCN-PEG3-VC-PFP ester Usage And Synthesis |
| Description | BCN-PEG3-VC-PFP Ester is a cleavable ADC linker. PFP ester can be reactive with amine-bearing molecule to form stable amide bond. The Val-Cit will specifically be cleaved by Cathepsin B. As this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. The BCN group can react with azide-tagged biomolecules. |
| | BCN-PEG3-VC-PFP ester Preparation Products And Raw materials |
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