(19E)-18-Demethoxy-16-hydroxygardneramine oxindole

(19E)-18-Demethoxy-16-hydroxygardneramine oxindole Basic information
Product Name:(19E)-18-Demethoxy-16-hydroxygardneramine oxindole
Synonyms:(19E)-18-Demethoxy-16-hydroxygardneramine oxindole;Chitosenine;Spiro[3H-indole-3,1'(5'H)-[3,7]methanoindolizin]-2(1H)-one, 6'-ethylidene-2',3',6',7',8',8'a-hexahydro-9'-hydroxy-9'-(hydroxymethyl)-4,5,7-trimethoxy-, (1'S,3'S,6'E,7'S,8'aS,9'R)-
CAS:56210-06-1
MF:C22H28N2O6
MW:416.47
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Mol File:56210-06-1.mol
(19E)-18-Demethoxy-16-hydroxygardneramine oxindole Structure
(19E)-18-Demethoxy-16-hydroxygardneramine oxindole Chemical Properties
Boiling point 655.0±55.0 °C(Predicted)
density 1.41±0.1 g/cm3(Predicted)
pka11.26±0.40(Predicted)
Safety Information
MSDS Information
(19E)-18-Demethoxy-16-hydroxygardneramine oxindole Usage And Synthesis
DescriptionA Gardneria alkaloid, chitosenine has recently been isolated from G. multiflora. It forms an amorphous white powder having no definite melting point and gives an ultraviolet spectrum in EtOH with an absorption maximum at 314 nm and a shoulder at 259 nm. Reaction with mesyl chloride yields the monomesylate with m.p. 161-7°C. When treated with anhydrous potassium carbonate in absolute dimethylformamide it yields the oxilane derivative. The structure has been elucidated from chemical analysis and spectroscopic data.
ReferencesSakaietal., Tetrahedron Lett., 715 (1975)
(19E)-18-Demethoxy-16-hydroxygardneramine oxindole Preparation Products And Raw materials
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