(R)-N-Boc-3-hydroxyadaMantylglycine manufacturers
|
| | (R)-N-Boc-3-hydroxyadaMantylglycine Basic information | | Uses |
| Product Name: | (R)-N-Boc-3-hydroxyadaMantylglycine | | Synonyms: | Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-diMethylethoxy)carbonyl]aMino]-3-hydroxy-, (αR)-;(alphaR)-alpha-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-hydroxytricyclo[3.3.1.1(3,7)]decane-1-acetic acid;(R)-N-Boc-3-hydroxyadaMantylglycine;(R)-N-Boc-2-(3-hydroxyadamant-1-yl)glycine;Boc-3-hydroxy-1-adamantyl-glycine;"(a-R)-a--[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-Tricyclo[3.3.1.13,7]decane-1-acetic acid";Boc-3-hydroxy-1-adamantyl-L-glycine;Tricyclo[3.3.1.13,7]decane-1-acetic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (αR)- | | CAS: | 1334321-39-9 | | MF: | C17H27NO5 | | MW: | 325.4 | | EINECS: | | | Product Categories: | | | Mol File: | 1334321-39-9.mol |  |
| | (R)-N-Boc-3-hydroxyadaMantylglycine Chemical Properties |
| Melting point | >280°C (dec.) | | Boiling point | 497.3±20.0 °C(Predicted) | | density | 1.296±0.06 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | | pka | 3.93±0.10(Predicted) | | form | Solid | | color | White to Off-White |
| | (R)-N-Boc-3-hydroxyadaMantylglycine Usage And Synthesis |
| Uses | Boc-3-hydroxy-1-adamantyl-glycine is an impurity of Saxagliptin (S143500), which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing. | | Uses | Boc-3-hydroxy-1-adamantyl-glycine is an impurity of Saxagliptin (S143500), which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing. |
| | (R)-N-Boc-3-hydroxyadaMantylglycine Preparation Products And Raw materials |
|
|
Tag:(R)-N-Boc-3-hydroxyadaMantylglycine(1334321-39-9)
Related Product Information
|
|
3-Hydroxy-1-AdaMantane Carboxylic Acid
Saxagliptin Impurity 34
Hydroxy Saxagliptin
2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1R,3R,5R)-
2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2R)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1R,3S,5R)-
(S) - N- Boc- adamantylglycine
Saxagliptin Impurity 16
2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3R,5S)-
1H-Cyclopropa[4,5]pyrrolo[1,2-a]pyrazine-3,6-dione, hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-, (1aS,4S,6aR,7aS)-
(1R,3S,5R)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXAMIDE 2,2,2-TRIFLUOROACETIC ACID
2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2R)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3S,5S)-
(1R,3R,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide 2,2,2-trifluoroacetate
1H-Pyrrole-1-carboxylic acid, 2-(aMinocarbonyl)-2,3-dihydro-, 1,1-diMethylethyl ester, (2S)-
(1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID
3H-Cyclopropa[4,5]pyrrolo[1,2-a]pyrazin-3-one, 6-aMino-1,1a,4,6a,7,7a-hexahydro-4-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)-, (1aS,4S,6aR,7aS)-
Saxagliptin
2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2R)-2-aMino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1R,3R,5R)-
Saxagliptin Impurity 15
|