依米地肽
| 中文名称 | 依米地肽 |
|---|---|
| 中文同义词 | 依米地肽;DELTA-SLEEP INDUCING PEPTIDE|依米地肽;DELTA睡眠诱导多肽;催睡眠肽;DELTA-SLEEP INDUCING肽;依米地肽, ≥97% (HPLC);依米地肽/DELTASLEEP-INDUCING PEPTIDE (RABBIT);睡眠诱导肽 |
| 英文名称 | DSIP |
| 英文同义词 | SLEEP INDUCING PEPTIDE;WAGGDASGE;TRP-ALA-GLY-GLY-ASN-ALA-SER-GLY-GLU;TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU;TRP-ALA-GLY-GLY-ASP-ALA-SER-GLY-GLU 4H2O;DELTA SLEEP INDUCING PEPTIDE;DELTA SLEEP-INDUCING PEPTIDE 4H2O;DSIP |
| CAS号 | 62568-57-4 |
| 分子式 | C35H48N10O15 |
| 分子量 | 848.82 |
| EINECS号 | 211-519-9 |
| 相关类别 | 肽;医药原料;细胞生物学;多肽中间体;细胞信号和神经生物学;原料药;多肽;生化试剂-蛋白质;Peptide;药物肽;库存;贝尔卡主打;试剂盒-Elisa试剂盒;标准品;药物多肽 |
| Mol文件 | 62568-57-4.mol |
| 结构式 |  |
依米地肽 性质
| 沸点 | 1522.7±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.458±0.06 g/cm3(Predicted) |
| 储存条件 | −20°C |
| 形态 | 粉末 |
| 酸度系数(pKa) | 3.18±0.10(Predicted) |
| 水溶解性 | Soluble in water at 0.5mg/ml |
| 序列 | H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH |
| InChIKey | ZRZROXNBKJAOKB-GFVHOAGBSA-N |
依米地肽是一种神经肽，具有抗氧化和抗焦虑作用。
In rabbit infused with δ-Sleep Inducing Peptide (DSIP), the spindle activity is increased, and heart and respiration rate are moderately decreased. δ-Sleep Inducing Peptide (DSIP) may act as a programming modulator at supra-operational level rather than as a transmitter at operational level. δ-Sleep Inducing Peptide (DSIP; 40 μg/kg, i.p.) increases catalase and superoxide dismutase (SOD) activities and malonic dialdehyde (MDA) concentration in the liver homogenate of rats subjected to acute stress, but the opposite effects are observed at 120, and 360 μg/kg.
多肽
依米地肽是由9种氨基酸组成的肽。这类多肽能够通过固相合成方法制备出来。在一些研究中证实，依米地肽能够起到改善、诱导睡眠的效果。参考质量标准
外观:白色粉末纯度(HPLC) ≥98.0%
醋酸根含量5.0%～12.0%
水分含量≤8.0%
肽含量≥80.0%
安全信息
| 安全说明 | 22-24/25 |
|---|---|
| WGK Germany | 3 |
| 提供商 | 语言 |
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英文
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