| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:α-Actinin
CAS:11003-00-2
Purity:~80% alpha-actinin basis (SDS-PAGE) Package:0.5mg, 500μg, 1mg, 5mg Remarks:A9776
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| Company Name: |
Shanghai Guchen Biotechnology Co., LTD
|
| Tel: |
021-34675735 19147740836 |
| Email: |
1986399151@qq.com |
| Products Intro: |
Product Name:α-Actinin from chicken gizzard
CAS:11003-00-2
Purity:~80% α-actinin basis (SDS-PAGE), ammonium sulfate suspension Package:1mg
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| Company Name: |
United States Biological
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| Tel: |
1-800-520-3011 |
| Email: |
sales@advtechind.com |
| Products Intro: |
Product Name:Alpha Actinin
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| | ALPHA-ACTININ Basic information |
| | ALPHA-ACTININ Chemical Properties |
| storage temp. | 2-8°C | | form | ammonium sulfate suspension |
| WGK Germany | 3 | | HS Code | 3504009000 |
| | ALPHA-ACTININ Usage And Synthesis |
| Uses | α-Actinin from chicken gizzard has been used:
- as an antigen to coat plates for the capture of anti-actinin antibody using enzyme-linked immunosorbent assay (ELISA) from tumor cell line clones
- in in vitro motility experiments to test its effect on actin filament movement
- to coat cantilevers for strengthening fluorescently labeled actin filaments in force measurement studies
| | General Description | α-Actinin exists as a rod-shaped antiparallel dimer with two elongated subunits. The domain region contains an N-terminal actin-binding domain with tandem calponin homology domains, a central tandem 3-helix motifs, and EF-hand motifs at C-terminus. It belongs to the spectrin superfamily and is localized in actin structures. | | Biochem/physiol Actions | α-Actinin binds actin and has the ability to crosslink actin cytoskeleton. It also plays a key role in the structural maintenance of the Z-disk of striated muscle. |
| | ALPHA-ACTININ Preparation Products And Raw materials |
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