| Company Name: |
Nanjing Peptide Biotech Ltd.
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| Tel: |
025-58361106-805 13082558573 |
| Email: |
liugang@njpeptide.com |
| Products Intro: |
Product Name:Bottromycin A(2)
CAS:15005-62-6
Purity:90%HPLC,95%HPLC,98%HPLC Package:5mg,20mg,100mg,250mg,500mg,1g
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| Company Name: |
ChemeGen 中国
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:Bottromycin A2
CAS:15005-62-6
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Bottromycin A2
CAS:15005-62-6
Purity:80% Package:1mg
|
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| | bottromycin A(2) Basic information |
| Product Name: | bottromycin A(2) | | Synonyms: | bottromycin A(2);b-Alanine, N-[(2S)-2-[[glycyl-(3R)-3-methyl-Lprolyl-L-valyl]amino]-1-imino-3,3-dimethylbutyl]-3-methyl-L-valyl-(bS)-b-methyl-L-phenylalanyl-3-(2-thiazolyl)-, methyl ester, cyclic (1')-imine,(3R)-;β-Alanine, N-[(2S)-2-[[glycyl-(3R)-3-methyl-L-prolyl-L-valyl]amino]-1-imino-3,3-dimethylbutyl]-3-methyl-L-valyl-(βS)-β-methyl-L-phenylalanyl-3-(2-thiazolyl)-, methyl ester, cyclic (1→1')-imine, (3R)- | | CAS: | 15005-62-6 | | MF: | C42H62N8O7S | | MW: | 823.07 | | EINECS: | | | Product Categories: | | | Mol File: | 15005-62-6.mol |  |
| | bottromycin A(2) Chemical Properties |
| Boiling point | 1061.3±65.0 °C(Predicted) | | density | 1.28±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Ether: soluble,Methanol: soluble, | | form | A solid | | pka | 12.18±0.46(Predicted) | | Water Solubility | Water: soluble |
| | bottromycin A(2) Usage And Synthesis |
| Biological Activity | Bottromycin A2 is an antibiotic originally isolated from Streptomyces.1 It blocks the binding of aminoacyl-tRNA to the A site of the 50S ribosome, inhibiting protein synthesis.2 Bottromycin A2 is active against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci with MIC values of 1 and 0.5 μg/ml, respectively. | | References | 1.Nakamura, S., Yajima, T., Lin, Y., et al.Isolation and characterization of bottromycins A2, B2, C2J. Antibiot. (Tokyo)20(1)1-5(1967)
2.Gouda, H., Kobayashi, Y., Yamada, T., et al.Three-dimensional solution structure of bottromycin A2: A potent antibiotic active against methicillin-resistant Staphylococcus aureus and vancomycin-resistant EnterococciChem. Pharm. Bull. (Tokyo)60(2)169-171(2012) |
| | bottromycin A(2) Preparation Products And Raw materials |
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