| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-Vinculin
Purity:affinity isolated antibody, buffered aqueous solution Package:200μL Remarks:V4139
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| | ANTI-VINCULIN Basic information |
| | ANTI-VINCULIN Chemical Properties |
| storage temp. | −20°C | | form | buffered aqueous solution |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 |
| | ANTI-VINCULIN Usage And Synthesis |
| Uses | Anti-vinculin antibody produced in rabbit has been used in following studies:
- immunofluorescence
- immuno-histology
- western blotting
| | Uses | Monoclonal Anti-Vinculin antibody produced in mouse has been used in:
- western blotting
- immunofluorescence staining
- immunohistochemistry
| | General Description | Monoclonal Anti-Vinculin (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. | | Biochem/physiol Actions | Vinculin (VCL) is a cytoskeletal protein, which plays a vital role in regulation of cell-to-cell and cell to matrix junctions. VCL facilitates normal embryonic development and cardiac function. Aberration or mutation of the gene leads to cardiomyopathy. VCL also plays a crucial role in cell migration and morphogenesis. VCL might facilitate the binding of integrins and cadherins to the actin cytoskeleton. Vinculin plays an important role in integrin αIIbβ3 signaling and function, which is required for platelet aggregation. |
| | ANTI-VINCULIN Preparation Products And Raw materials |
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