(13E)-7β-Hydroxy-19-methoxy-19-oxo-N-(2-hydroxyethyl)-N-methylcass-13(15)-en-16-oic amide

(13E)-7β-Hydroxy-19-methoxy-19-oxo-N-(2-hydroxyethyl)-N-methylcass-13(15)-en-16-oic amide Basic information
Product Name:(13E)-7β-Hydroxy-19-methoxy-19-oxo-N-(2-hydroxyethyl)-N-methylcass-13(15)-en-16-oic amide
Synonyms:(13E)-7β-Hydroxy-19-methoxy-19-oxo-N-(2-hydroxyethyl)-N-methylcass-13(15)-en-16-oic amide;(1S,4bα,7E,8aβ,10aα)-Tetradecahydro-9β-hydroxy-7-[[N-(2-hydroxyethyl)-N-methylcarbamoyl]methylene]-1α,4aβ,8α-trimethylphenanthrene-1β-carboxylic acid methyl ester;Norcassamidide;1-Phenanthrenecarboxylic acid, tetradecahydro-9-hydroxy-7-[2-[(2-hydroxyethyl)methylamino]-2-oxoethylidene]-1,4a,8-trimethyl-, methyl ester, (1S,4aR,4bS,7E,8R,8aS,9S,10aR)-
CAS:40445-00-9
MF:C24H39NO5
MW:421.57
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Mol File:40445-00-9.mol
(13E)-7β-Hydroxy-19-methoxy-19-oxo-N-(2-hydroxyethyl)-N-methylcass-13(15)-en-16-oic amide Structure
(13E)-7β-Hydroxy-19-methoxy-19-oxo-N-(2-hydroxyethyl)-N-methylcass-13(15)-en-16-oic amide Chemical Properties
Melting point 115°C
Boiling point 579.6±50.0 °C(Predicted)
density 1.149±0.06 g/cm3(Predicted)
pka14.48±0.10(Predicted)
Safety Information
MSDS Information
(13E)-7β-Hydroxy-19-methoxy-19-oxo-N-(2-hydroxyethyl)-N-methylcass-13(15)-en-16-oic amide Usage And Synthesis
DescriptionThis alkaloid obtained from the bark of Erythrophleum guineense and E. chlorostachys was originally named norcassamidine, the latter name having been given to another base from the same source (q.v.). Norcassamidide has [α]20D - 22.5° (c 0.65, EtOH). The structure has been elucidated from the NMR and mass spectra.
ReferencesLoder et al., Tetrahedron Lett., 5069 (1972)
(13E)-7β-Hydroxy-19-methoxy-19-oxo-N-(2-hydroxyethyl)-N-methylcass-13(15)-en-16-oic amide Preparation Products And Raw materials
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