| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:Abacavir 5'-Phosphate
CAS:136470-77-4
Package:2.5Mg,25Mg
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:Abacavir 5’-Phosphate
CAS:136470-77-4
Purity:> 95% Remarks:https://www.bocsci.com/product/abacavir-5-phosphate-cas-136470-77-4-465951.html
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| | Abacavir 5’-Phosphate Basic information |
| | Abacavir 5’-Phosphate Chemical Properties |
| Melting point | 189-194°C (dec.) | | Boiling point | 749.3±70.0 °C(Predicted) | | density | 1.93±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Methanol, Water | | pka | 1.91±0.10(Predicted) | | form | Solid | | color | White |
| | Abacavir 5’-Phosphate Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | Abacavir 5’-Phosphate (Abacavir - In House Impurity) is a metabolite of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. | | Definition | ChEBI: Abacavir monophosphate is the organic phosphate that is the 5'-monophosphate of abacavir. It has a role as a metabolite. It is a member of 2,6-diaminopurines and an organic phosphate. It is functionally related to an abacavir. |
| | Abacavir 5’-Phosphate Preparation Products And Raw materials |
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