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TETANUS TOXIN

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Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Products Intro: Product Name:Tetanus toxin
CAS:676570-37-9
Package:25μg Remarks:T3194
Company Name: Wuhan FengyaoTonghui Chemical Products Co., Ltd.  
Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Products Intro: Product Name:tetanus toxin from clostridium tetani
CAS:676570-37-9
Purity:99% HPLC Package:5KG;1KG
Company Name: Portail Substances Chimiques  
Tel: 10 20 0000
Email: webmestre-substances@ineris.fr
Products Intro: CAS:676570-37-9
Company Name: Riedel-de Haen AG  
Tel: 800 558-9160
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Products Intro: Product Name:Tetanus toxin from Clostridium tetani
CAS:676570-37-9
Company Name: SIGMA-RBI  
Tel: 800 736 3690 (Orders)
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TETANUS TOXIN Basic information
Product Name:TETANUS TOXIN
Synonyms:tetanus toxin from clostridium tetani
CAS:676570-37-9
MF:
MW:0
EINECS:
Product Categories:BacteriaNeurotransmission;Glycinergics;Cell Signaling and Neuroscience;Neurotransmitters;Toxins and Venoms
Mol File:Mol File
TETANUS TOXIN Structure
TETANUS TOXIN Chemical Properties
storage temp. 2-8°C
solubility H2O: soluble
Safety Information
Hazard Codes T+
Risk Statements 26/27/28
Safety Statements 28-36/37/39-45-36/37
RIDADR UN 3462 6.1/PG 1
WGK Germany 3
MSDS Information
TETANUS TOXIN Usage And Synthesis
UsesTetanus toxin is the tetanus toxin produced by the anaerobic bacillus?Clostridium tetani.
UsesTetanus toxin from Clostridium tetani has been used as the exocytosis inhibitor/Golgi-dependent secretion to examine whether secretory carrier membrane protein (SCAMP5) stimulated α-synuclein secretion via the conventional Golgi-dependent pathway. It has also been used in peripheral blood mononuclear cells (PBMCs) culture for?T?cell?proliferation screening.
General DescriptionTetanus toxin is also known as tetanospasmin. It is a 150-kDa protein, produced by Clostridium tetani. This protein consists of a light and a heavy chain.
Biochem/physiol ActionsBinds to polysialogangliosides acceptors on surface of all peripheral presynaptic nerve terminals. Internalized by receptor-mediated endocytosis and carried to spinal cord and brain by transsynaptic retrograde transport. Blocks the release of glycine from inhibitory interneurons of the spinal cord. Cleaves synaptobrevin (VAMP-2), and blocks synaptic vesicle exocytosis in vivo.
TETANUS TOXIN Preparation Products And Raw materials
Tag:TETANUS TOXIN(676570-37-9) Related Product Information
N-BUTYLISOCYANIDE Aluminum acetylacetonate PHENYLSELENOL 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE COBALT(II) ACETYLACETONATE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Tosylmethyl isocyanide SALCOMINE Ferric acetylacetonate 2,4-PENTANEDIONE, SILVER DERIVATIVE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Ethyl isocyanoacetate Cupric acetylacetonate Benzyl isocyanide Tris(2,4-pentanedionato)chroMiuM(III) METHYL ISOCYANOACETATE TERT-BUTYL ISOCYANIDE