| Company Name: |
Guangzhou Isun Pharmaceutical Co., Ltd
|
| Tel: |
020-39119399 18927568969 |
| Email: |
isunpharm@qq.com |
| Products Intro: |
Product Name:Aconitase from porcine heart
CAS:9024-25-3
Purity:BR Package:1mg; 10mg; 100mg; 1G; 10G
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Aconitase from porcine heart
CAS:9024-25-3
Purity:Aconitase from porcine heart Package:150MG Remarks:A5384-150MG
|
| Company Name: |
Guangzhou Tomums Life Science Co., Ltd.
|
| Tel: |
020-31155029 18902330969 |
| Email: |
sales@tomums.cn |
| Products Intro: |
Product Name:Aconitase from porcine heart
CAS:9024-25-3
Package:150MG;250MG
|
| Company Name: |
Wuhan Chemstan Biotechnology Co., Ltd.
|
| Tel: |
15926423062 |
| Email: |
422450190@qq.com |
| Products Intro: |
Product Name:Human ACO1 Protein, His Tag
Purity:>90% as determined by SDS-PAGE Package:50μg, 100μg
|
|
| | ACONITASE Basic information |
| Product Name: | ACONITASE | | Synonyms: | EC 4.2.1.3;CITRATE [ISOCITRATE] HYDROLYASE;ACONITASE;ACONITATE HYDRATASE;aconitase from porcine heart;ACONITASE, FROM PIG HEART;Aconitate hydratase, Citrate (isocitrate) hydrolyase;Aconitase, Citrate (isocitrate) hydro-lyase | | CAS: | 9024-25-3 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | enzyme | | Mol File: | Mol File | ![ACONITASE Structure]() |
| | ACONITASE Chemical Properties |
| Safety Statements | 22-24/25 | | WGK Germany | 3 | | Toxicity | Aconitase is the enzyme that reversibly interconverts
citric acid, cis-aconitic acid, and isocitric acid in the
tricarboxylic acid cycle (TCA) (formerly known as the citric
acid or Krebs cycle) by dehydration and hydration reactions.
Aconitase is the target for fluoroacetate, a potent rodenticide,
that condenses with oxaloacetate to yield an aconitase inhibitor
(fluorocitric acid), with resultant accumulation of citric acid
and thus blockage of the TCA cycle, leading to an inhibition
of aerobic energy production. |
| | ACONITASE Usage And Synthesis |
| Uses | Aconitase may be usefull in diabetes research as well as to study structural conservation between iron-responsive element binding proteins (IRE-BP) and isomerases . | | Biochem/physiol Actions | Aconitase catalyses the stereo-specific isomerization of citrate to isocitrate via cis-aconitate in the tricarboxylic acid cycle. Aconitase is inhibited by cyanide, sulfide and copper and mercury at low concentrations. It is competitively inhibited by trans-aconitate. Aconitase contains an internal Fe-S cluster which is responsible for its activity. |
| | ACONITASE Preparation Products And Raw materials |
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