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| | Methyl 1-acetyl-2-oxoindoline-6-carboxylate Basic information |
| Product Name: | Methyl 1-acetyl-2-oxoindoline-6-carboxylate | | Synonyms: | Methyl 1-acetyl-2-oxoindoline-6-carboxylate;1-Acetyl-2,3-dihydro-2-oxo-1H-indole-6-carboxylic acid methyl ester;1-acetyl-2-oxo-2,3-dihydro-1H-indole-6-carboxylic acid methyl ester;Nintedanib-002;methyl-1-acetyl2-oxoindole-6-carboxylate;Nintedanib impurity 1/Methyl 1-Acetyl-2-oxoindoline-6-carboxylate;1H-Indole-6-carboxylic acid, 1-acetyl-2,3-dihydro-2-oxo-, methyl ester;methyl 1-acetyl-2-oxo-3H-indole-6-carboxylate | | CAS: | 676326-36-6 | | MF: | C12H11NO4 | | MW: | 233.22 | | EINECS: | | | Product Categories: | | | Mol File: | 676326-36-6.mol |  |
| | Methyl 1-acetyl-2-oxoindoline-6-carboxylate Chemical Properties |
| Boiling point | 489.5±45.0 °C(Predicted) | | density | 1.330 | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | -1.94±0.20(Predicted) | | color | Off-White to Pale Red |
| | Methyl 1-acetyl-2-oxoindoline-6-carboxylate Usage And Synthesis |
| Uses | Methyl 1-Acetyl-2-oxoindoline-6-carboxylate is a reagent used in the preparation of Nintedanib (N478290), an angiokinase inhibitor and is used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy. |
| | Methyl 1-acetyl-2-oxoindoline-6-carboxylate Preparation Products And Raw materials |
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