Company Name: |
J & K SCIENTIFIC LTD.
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Tel: |
010-82848833 400-666-7788 |
Email: |
jkinfo@jkchemical.com |
Products Intro: |
Product Name:Fexofenadine-d10 Hydrochloride CAS:1215821-44-5 Package:10Mg,1Mg
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Company Name: |
Cato Research Chemicals Inc.
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Tel: |
020-81960175 |
Email: |
min.he@cato-chem.com |
Products Intro: |
Product Name:Fexofenadine-d10 Hydrochloride CAS:1215821-44-5 Purity:95% Package:25Mg, 50Mg
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Company Name: |
Hefei Molake Biotechnology Co., Ltd.
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Tel: |
0551-66336380 18956014586 |
Email: |
983438788@qq.com |
Products Intro: |
Product Name:Fexofenadine-d10 HCl CAS:1215821-44-5 Purity:98% Package:10mg,100mg,1g,10g
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Company Name: |
Energy Chemical
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Tel: |
021-58432009 400-005-6266 |
Email: |
marketing1@energy-chemical.com |
Products Intro: |
Product Name:Fexofenadine-d10 Hydrochloride CAS:1215821-44-5 Purity:NULL Package:10mg;1mg Remarks:NULL
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| Fexofenadine-d10 Hydrochloride Basic information |
| Fexofenadine-d10 Hydrochloride Chemical Properties |
Melting point | 150-155°C | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | solubility | DMSO (Slightly), Methanol (Slightly) | form | Solid | color | White to Off-White | Stability: | Hygroscopic |
| Fexofenadine-d10 Hydrochloride Usage And Synthesis |
Description | Fexofenadine-d10 is intended for use as an internal standard for the quantification of fexofenadine by GC- or LC-MS. Fexofenadine is a histamine H1 receptor antagonist (Ki = 10 nM). It reverses contraction of isolated rat tracheal strips induced by acetyl-β-methylcholine . Fexofenadine inhibits expression of IL-8 in TNF-α-stimulated HCT116 and COLO 205 cells. Oral administration of fexofenadine (2 and 10 mg/kg) reduces severity of colitis and phospho-IκB kinase activation in a mouse model of colitis induced by dextran sulfate sodium (DSS; ). | Uses | Fexofenadine-d10 Hydrochloride is the labeled analogue of Fexofenadine Hydrochloride (F322490), the active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist. |
| Fexofenadine-d10 Hydrochloride Preparation Products And Raw materials |
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