| Company Name: |
Shanghai Aladdin Bio-Chem Technology Co.,LTD
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| Tel: |
18521735133 18521732826; |
| Email: |
market@aladdin-e.com |
| Products Intro: |
Product Name:D-erythro-sphingosine-d7
CAS:1246304-34-6
Purity:>99% Package:10mg/RMB 17339.00;1mg/RMB 3863.90;5mg/RMB 9734.00
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| Company Name: |
Codow Chemical Co.,Ltd.
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| Tel: |
18620099427 |
| Email: |
amy@howeipharm.com |
| Products Intro: |
Product Name: D-erythro-sphingosine-d7
CAS:1246304-34-6
Purity:>99% Package:1MG;2.5MG;5MG
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| Company Name: |
Chengdu Dianchun Technology Co., Ltd
|
| Tel: |
400-1166-196 18502815961 |
| Email: |
cdhxsj@163.com |
| Products Intro: |
Product Name:D-erythro-sphingosine-d7
CAS:1246304-34-6
Purity:99% HPLC Package:10g;50g;100g;500g;1kg;5kg;25kg
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| Company Name: |
Combiphos (Shanghai) Biological Technology Co., Ltd.
|
| Tel: |
021-65232103 17602124823 |
| Email: |
combiphos@vip.qq.com |
| Products Intro: |
Product Name:(2S,3R,4E)-2-aminooctadec-4-ene-16,16,17,17,18,18,18-d7-1,3-diol
CAS:1246304-34-6
Purity:95% HPLC Package:25 mg;250 mg;1.0 g;5.0 g Remarks:DS112
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| D-erythro-sphingosine-d7 Basic information |
| Product Name: | D-erythro-sphingosine-d7 | | Synonyms: | D-erythro-sphingosine-d7 ;D-ERYTHRO-SPHINGOSINE-D7 ;SPHINGOSINE-D7;sphingosine-d7;D-erythro-sphingosine-d7;Sphingosine-d7 (d18:1);(2S,3R,4E)-2-aminooctadec-4-ene-16,16,17,17,18,18,18-d7-1,3-diol | | CAS: | 1246304-34-6 | | MF: | C18H30D7NO2 | | MW: | 306.535012446 | | EINECS: | | | Product Categories: | | | Mol File: | 1246304-34-6.mol |  |
| D-erythro-sphingosine-d7 Chemical Properties |
| solubility | DMF: 20 mg/ml; DMSO: 2 mg/ml; Ethanol: miscible | | form | A crystalline solid |
| D-erythro-sphingosine-d7 Usage And Synthesis |
| Description | Sphingosine-d7 (d18:1) is intended for use as an internal standard for the quantification of sphingosine (d18:1) by GC- or LC-MS. Sphingosine (d18:1) is formed primarily from the breakdown of ceramide.1 Sphingosine (d18:1) inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase.1 Phosphorylation of sphingosine (d18:1) by sphingosine kinases 1 and 2 (SPHK1, SPHK2) produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.2,3,4 | | References | 1. Hannun, Y.A., Luberto, C., and Argraves, K.M. Enzymes of sphingolipid metabolism: From modular to integrative signaling Biochemistry 40(16),4893-4903(2001).
2. Takuwa, Y., Takuwa, N., and Sugimoto, N. The Edg family G protein-coupled receptors for lysophospholipids: Their signaling properties and biological activities J. Biochem. 131(6),767-771(2002).
3. Ishii, I., Fukushima, N., Ye, X., et al. Lysophospholipid receptors: Signaling and biology Annu. Rev. Biochem. 73,321-354(2004).
4. Kluk, M.J., and Hla, T. Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors Biochim. Biophys. Acta 1582(1-3),72-80(2002). |
| D-erythro-sphingosine-d7 Preparation Products And Raw materials |
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