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| | Saccharin 1-methylimidazole (SMI) Basic information |
| Product Name: | Saccharin 1-methylimidazole (SMI) | | Synonyms: | Saccharin 1-methylimidazole (SMI);Saccharin 1-methylimidazole;Saccharin 1 methylimidazole,Inhibitor,Saccharin 1-methylimidazole,inhibit,Saccharin 1methylimidazole,DNA/RNA Synthesis | | CAS: | 482333-74-4 | | MF: | C11H11N3O3S | | MW: | 265.29 | | EINECS: | | | Product Categories: | | | Mol File: | 482333-74-4.mol |  |
| | Saccharin 1-methylimidazole (SMI) Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO:52.67(Max Conc. mg/mL);198.54(Max Conc. mM)
Water:53.0(Max Conc. mg/mL);199.78(Max Conc. mM)
Ethanol:31.5(Max Conc. mg/mL);118.74(Max Conc. mM)
DMF:5.0(Max Conc. mg/mL);18.85(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);37.69(Max Conc. mM) | | form | A solid |
| | Saccharin 1-methylimidazole (SMI) Usage And Synthesis |
| Description | Saccharin 1-methylimidazole is a chemical activator that has been commonly used in solid-phase synthesis of DNA and RNA oligonucleotides. It catalyzes the phosphoramidite coupling reaction of the 5'' hydroxy of immobilized nucleosides and the amine group of nucleoside phosphoramidite. Saccharin 1-methylimidazole has been used to synthesize single-stranded DNA (ssDNA) oligonucleotides that are resistant to nuclease digestion. | | Uses | Saccharin 1-Methylimidazole is a reagent used for nucleic acid synthesis (1,2). |
| | Saccharin 1-methylimidazole (SMI) Preparation Products And Raw materials |
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