| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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| Products Intro: |
Product Name:bpV(phen)
CAS:42494-73-5
Purity:>=95% V basis Package:5mg, 25mg Remarks:SML0889
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| | BPV(PHEN) Basic information |
| Product Name: | BPV(PHEN) | | Synonyms: | POTASSIUM BISPEROXO(1,10-PHENANTHROLINE)OXOVANADATE (V);BPV(PHEN);K[VO(O2)2C12H8N2] 3H2O;Potassium Bisperoxo(1,10-phenanthroline)oxovanadate (V) trihydrate;bpV(phen) - CAS 42494-73-5 - Calbiochem | | CAS: | 42494-73-5 | | MF: | C12H8KN2O5V | | MW: | 350.24 | | EINECS: | | | Product Categories: | | | Mol File: | 42494-73-5.mol |  |
| | BPV(PHEN) Chemical Properties |
| storage temp. | -20°C | | solubility | H2O: soluble20mg/mL, clear | | form | Yellow solid | | color | faint yellow to dark yellow |
| | BPV(PHEN) Usage And Synthesis |
| General Description | The water content varies from lot to lot and is supplied on the label along with the lot-specific molecular weight. | | Biochem/physiol Actions | bpV(phen) is an insulin receptor kinase (IRK) activator and an inhibitor of protein phosphotyrosine phosphatases with selectivity for PTEN, phosphatase and tensin homolog, a tumour suppressor phosphatase involved in cell cycle regulation. IC50 values for bpV(phen) are 38 nM for PTEN compared to 343 nM for PTPβ and 920 nM for PTP-1β. bpV(phen) has anti-inflammatory effects in oxidative stress including inhibitory effects on oxidative stress-induced cardiomyocyte injury that may be partially modulated by the action of ROS on PTEN. It may also be involved in differentiation. |
| | BPV(PHEN) Preparation Products And Raw materials |
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