8-叠氮酰苷-5'-三磷酸钠
| 中文名称 | 8-叠氮酰苷-5'-三磷酸钠 |
|---|---|
| 中文同义词 | 8-叠氮酰苷-5'-三磷酸钠 |
| 英文名称 | 8-AZIDOADENOSINE 5'-TRIPHOSPHATE, SODIUM SALT |
| 英文同义词 | 8-azidoadenosine-5’-o-triphosphate(8-n3-atp),sodiumsalt;8-azidoadenosine5’-triphosphate;8-azidoadenosine5’-triphosphatesodium;8-AZIDOADENOSINE 5'-TRIPHOSPHATE, SODIUM SALT;8-AZIDOADENOSINE-5'-O-TRIPHOSPHATE SODIUM SALT;8-N3-ATP SODIUM SALT;8-Azido-D-adenosine5'-triphosphatesodiumsalt;Adenosine 5'-(tetrahydrogen triphosphate), 8-azido- |
| CAS号 | 53696-59-6 |
| 分子式 | C10H15N8O13P3 |
| 分子量 | 548.19 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 53696-59-6.mol |
| 结构式 |  |
8-叠氮酰苷-5'-三磷酸钠 性质
8-Azido-ATP 是一个光解性的核苷酸类似物，用于鉴定蛋白，如依赖于 DNA 的 RNA 聚合酶。
8-Azido-ATP can be used to identify the viral RNA polymerase on the basis of the ability of the analog to inhibit transcription activity associated with rotavirus particles on exposure to UV light.
8-Azido-ATP (azido-ATP) decreases viral transcription in a dose-dependent manner.
8-Azido-ATP blocks Kir6.2ΔC26 currents rather less potently than ATP, half-maximal inhibition (Ki) occurring at 2.8 ± 0.4 mM (n = 6) compared with 172 ± 7 mM for ATP (n = 6). The Hill coefficients were 0.9 ± 0.2 for 8-azido-ATP and 1.3 ± 0.1 for ATP.
安全信息
| 危险品标志 | Xi |
|---|---|
| 海关编码 | 2934999090 |