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alpha-Solanine

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Company Name: Finetech Industry Limited
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Products Intro: Product Name:ALPHA-SOLANINE
CAS:20562-02-1
Purity:98% Package:1g,10g,25g,500g,1kg
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:Alpha-Solanine
CAS:20562-02-1
Purity:HPLC>=98% Package:5mg
Company Name: Chengdu Biopurify Phytochemicals Ltd.
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Email: sales@biopurify.com
Products Intro: Product Name:Alpha-Solanin
CAS:20562-02-1
Purity:0.98 Package:10mg;20mg;50mg;100mg;500mg Remarks:10gg
Company Name: BOC Sciences
Tel: +1-631-485-4226
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Products Intro: Product Name:a-Solanine
CAS:20562-02-1
Remarks:BOC Sciences also provides custom synthesis services for a-Solanine.
Company Name: Shaanxi Dideu Medichem Co. Ltd
Tel: +86-029-81138252 +86-18789408387
Email: 1057@dideu.com
Products Intro: Product Name:α-Solanine
CAS:20562-02-1
Purity:99% Package:1KG;1USD

alpha-Solanine manufacturers

  • α-Solanine
  • α-Solanine  pictures
  • $1.00 / 1KG
  • 2020-05-10
  • CAS: 20562-02-1
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 20T
alpha-Solanine Basic information
Product Name:alpha-Solanine
Synonyms:SOLATUNIN;SOLATUNINE;beta-d-galactopyranoside,(3beta)-solanid-5-en-3-ylo-6-deoxy-alpha-l-mannopyra;POTATOGLYCOALKALOIDS;a-Solanine;alpha-solanin from potato sprouts;A-solanine from potato sprouts;alpha-SOLANINE tlc
CAS:20562-02-1
MF:C45H73NO15
MW:868.07
EINECS:243-879-8
Product Categories:Asymmetric Synthesis;Chiral Building Blocks;Complex Molecules;Alkaloids
Mol File:20562-02-1.mol
alpha-Solanine Structure
alpha-Solanine Chemical Properties
Melting point 285℃ (dec.)
Boiling point 780.78°C (rough estimate)
density 1.40±0.1 g/cm3 (20 ºC 760 Torr)
refractive index 1.5280 (estimate)
storage temp. −20°C
solubility Methanol (Slightly, Heated), Pyridine (Slightly, Sonicated), Water (Slightly, Heated)
form Solid
pka6.66(at 15℃)
color White to Off-White
Water Solubility 26.04mg/L(15 ºC)
Merck 13,8779
BRN 77607
InChIKeyZGVSETXHNHBTRK-MUEWWJAYNA-N
LogP5.670 (est)
Safety Information
Hazard Codes Xn
Risk Statements 22
Safety Statements 1-25-45-24/25
RIDADR 1544
WGK Germany 3
RTECS WF0250000
10
HazardClass 6.1(b)
PackingGroup III
HS Code 29399990
Hazardous Substances Data20562-02-1(Hazardous Substances Data)
MSDS Information
ProviderLanguage
SigmaAldrich English
alpha-Solanine Usage And Synthesis
DescriptionThis steroidal alkaloid is present in several Solanum species including S. nigrum, S. Iycopersicum (tomato) and S. tuberosum (potato). The base crystallizes in slender needles and shrinks markedly at 235°C. It has [α]20D - 59.45° (pyridine) or - 42.16° (dilute HCl) and is readily soluble in hot EtOH, sparingly so in H20 and virtually insoluble in CHCl 3 or Et2 0. The salts are mostly amorphous although a crystalline hydrochloride has been prepared with m.p. 212°C (dec.). It is not affected by alkalies but mineral acids hydrolyze it to solanidine (q.v.) and one mole each of dextrose, galactose and rhamnose.
Pharmacologically, the alkaloid is a protoplasmic poison and a powerful haemolytic. Poisoning by potatoes sometimes occurs although the results are not usually fatal. The symptoms are nausea, headache, emesis and gastritis. With large doses parenchymatous nephritis and haemoglobinuria occurs with, at times, paralysis of the central nervous system and cardiac arrest. The alkaloid also possesses local irritant properties.
Chemical PropertiesWhite solid
Usesα-Solanine is produced as a by product in the synthesis of α-Chaconine. α-Chaconine is a glycoalkaloid displaying nerve toxin activity. Potential antifungal activity.
DefinitionChEBI: A glycoalkaloid poison found in species of the nightshade family (Solanaceae), such as the potato (Solanum tuberosum). It is a trisccharide derivative of solanidine [(22beta)-solanid-5-en-3beta-ol].
benefitsIt has been revealed that α-solanine possesses potential chemotherapeutic action against cancers in several organs, including lung, breast, esophagus, prostate, and liver, as well as acute lymphocytic leukemia. α-solanine also has potential anti-inflammatory properties[1].
General DescriptionThis substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
HazardA poison.
Side effects A small amount of α-solanine can cause common symptoms such as dizziness, nausea, abdominal pain, vomiting, and diarrhea. Excessive consumption of α-solanine can lead to convulsions, coma, and even death. Animal studies have shown that α-solanine can damage the reproductive system[1].
Purification MethodsRecrystallise -solanine from EtOH, 85% aqueous EtOH, MeOH or aqueous MeOH as dihydrate m 276-278o. It solubility in H2O is 25mg/L and 5% in pyridine, but it is very soluble in Et2O and CHCl3. The hydrochloride is gummy or amorphous but has been crystallised (m ~212o dec). It has insecticidal properties. [Kuhn et al. Chem Ber 88 1492 1955, Beilstein 21 III/IV 1402.]
ReferencesDesfosses.,lahresb., 2, 114 (1820)
Firbas., Monatsh., 10, 541 (1889)
Cazeneuve, Breteau., Compt. rend., 128,887 (1899)
Davis., Pharm. I., 15, 160 (1902)
Wittman., Monatsh., 26,445 (1905)
Colombano., Gazzetta, 38, 19 (1908)
Zemplen, Gerecs., Ber., 61,2294 (1928)
Schopf, Herrmann., ibid, 66, 298 (1933)
Oddo, Caronna., ibid, 67,446 (1934)
References[1] Zhilong Chen. “α-Solanine Causes Cellular Dysfunction of Human Trophoblast Cells via Apoptosis and Autophagy.” Toxins (2021).
alpha-Solanine Preparation Products And Raw materials
Tag:alpha-Solanine(20562-02-1) Related Product Information
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