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Postion:Product Catalog >API>Antineoplastic agents>Natural sources of antineoplastic> DEMECOLCINE
	DEMECOLCINE
  • 	DEMECOLCINE
  • 	DEMECOLCINE

DEMECOLCINE NEW

Price $8 $5 $1
Package 1KG 25KG 100KG
Min. Order: 1KG
Supply Ability: g-kg-tons, free sample is available
Update Time: 2024-04-09

Product Details

Product Name: DEMECOLCINE CAS No.: 477-30-5
Min. Order: 1KG Purity: 99%
Supply Ability: g-kg-tons, free sample is available Release date: 2024/04/09
Lead time: In stock, ready for shipment In stock: bag/bottle/drum/IBC
COA, MSDS: Available, contact us for details Origin: Manufacturer, advantage product
Origin: By express, by air, by sea NAME: Sun

1. Materials information

Names

Name(-)-demecolcine
SynonymMore Synonyms

 (-)-Demecolcine Biological Activity

DescriptionColcemid (Demecolcine), a derivative of colchicine, is a potent mitotic inhibitor[1][2]. Colcemid binds to the protein tubulin and arrest cells in metaphase for karyotyping assays. Colcemid incuces cell apoptosis and can be used for cancer research[2].
Related Catalog
Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin
Research Areas >> Inflammation/Immunology
Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
References

[1]. T Tsuchida, et al. Colcemid-induced apoptosis of cultured human glioma: electron microscopic and confocal laser microscopic observation of cells sorted in different phases of cell cycle. Cytometry. 1998 Apr 1;31(4):295-9.

[2]. Ashley M Rozario, et al. Ultra-Low Colcemid Doses Induce Microtubule Dysfunction as Revealed by Super-Resolution Microscopy. Bioexiv.

 Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point625.5±55.0 °C at 760 mmHg
Melting Point73-75ºC
Molecular FormulaC21H25NO5
Molecular Weight371.427
Flash Point332.1±31.5 °C
Exact Mass371.173279
PSA66.02000
LogP1.52
Vapour Pressure0.0±1.8 mmHg at 25°C
Index of Refraction1.582



2. Packaging of materials

  • For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

  • For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                             Or smaller package 1kg/bottle, 10kgs/bottle as request. 


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3. Shipping & Delivery

  • By Express

Provide door to door service

Suitable for goods under 50kg

Delivery: 3-7 days

Cost: low cost

Article illustration


  • By Air

Provide airport to airport service

Suitable for goods over 50kg

Delivery: 3-14 days

Cost: high cost

Article illustration


  • By Sea

Provide seaport to seaport service

Suitable for goods over 100kg

Delivery: 2-45 days

Cost: low cost

Article illustration


4. Contact information

For more details, pls contact us freely.

Email address: sun@fdachem.com

Mob: 86 13526505137

WhatsApp/Skype/Wechat/LINE: 8613526505137





















Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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  • Since: 2023-02-10
  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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