Magnesium ascorbyl phosphate NEW
| Price | $8 | $5 | $1 |
| Package | 1KG | 25KG | 100KG |
| Min. Order: | 1KG |
| Supply Ability: | g-kg-tons, free sample is available |
| Update Time: | 2024-04-09 |
Product Details
| Product Name: Magnesium ascorbyl phosphate | CAS No.: 113170-55-1 |
| Min. Order: 1KG | Purity: 99% |
| Supply Ability: g-kg-tons, free sample is available | Release date: 2024/04/09 |
| Lead time: In stock, ready for shipment | In stock: bag/bottle/drum/IBC |
| COA, MSDS: Available, contact us for details | Origin: Manufacturer, advantage product |
| Origin: By express, by air, by sea | NAME: Sun |
1. Materials information
| Name | L-Ascorbic acid 2-phosphate sesquimagnesium salt hydrate |
|---|---|
| Synonym | More Synonyms |
| Description | L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression[1]. L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate magnesium (2-Phospho-L-ascorbic acid magnesium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation[2][3]. |
|---|---|
| Related Catalog | Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease |
| Target | IC50: alkaline phosphatase (ALP); collagen formation; runx2A[2][3] |
| In Vitro | L-Ascorbic acid 2-phosphate (0.1-1.5 mM; 2 to 3 weeks with medium exchange every 2 to 3 days) significantly stimulates cell growth, whereas addition of l-Ascorbic acid (Asc) achieves only weak growth stimulation. A combination of Asc-2P and bFGF significantly increases cell growth, but supplementation with EGF and/or insulin does not have any additional effect [1]. L-Ascorbic acid 2-phosphate (50 µM-250 µM) is needed for the effective osteogenic differentiation of human adipose stem cells (hASCs), and higher concentrations of AsA2-P results in increased runx2 expression and ALP activity. The highest proliferation, ALP activity and runx2 expression is achieved with 150 µM AsA2-P and 10 nM dexamethasone (Dex), and 250 µM AsA2-P and 5 nM Dex[3]. Cell Viability Assay[1] Cell Line: Human corneal endothelial cells (HCECs) Concentration: 0.1 mM; 0.3 mM; 1.5 mM Incubation Time: 2 to 3 weeks with medium exchange every 2 to 3 days Result: Stimulated HCEC cells growth. |
| References | [1]. Shima N, et al. Increased proliferation and replicative lifespan of isolated human corneal endothelial cells with L-ascorbic acid 2-phosphate.Invest Ophthalmol Vis Sci. 2011 Nov 7;52(12):8711-7. [2]. Kurata S, et al. Epidermal growth factor inhibits transcription of type I collagen genes and production of type I collagen in cultured human skin fibroblasts in the presence and absence of L-ascorbic acid 2-phosphate, a long-acting vitamin C derivative.J Biol Chem. 1991 May 25;266(15):9997-10003. [3]. Kyllönen L, et al. Effects of different serum conditions on osteogenic differentiation of human adipose stem cells in vitro.Stem Cell Res Ther. 2013 Feb 15;4(1):17. |
| Molecular Formula | C6H9O9P.3/2Mg |
|---|---|
| Molecular Weight | 278.393 |
| Exact Mass | 277.967804 |
| PSA | 169.22000 |
L-Ascorbic acid 2-phosphate magnesium MSDS(Chinese) |
| Hazard Codes | Xi |
|---|---|
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36/37/39 |
| HS Code | 2835100000 |
| HS Code | 2835100000 |
|---|
| trimagnesium,[(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-oxido-5-oxo-2H-furan-4-yl] phosphate |
| L-Ascorbic Acid 2-Phosphate Sesquimagnesium Salt Hydrate |
| Magnesium (5R)-5-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-2-oxo-2,5-dihydro-3-furanyl phosphate |
| MFCD08063372 |
. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
By Express
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
By Air
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
By Sea
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
For more details, pls contact us freely.
Email address: sun@fdachem.com
Mob: 86 13526505137
WhatsApp/Skype/Wechat/LINE: 8613526505137
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China
- Since: 2023-02-10
- Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro