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Postion:Product Catalog >API>Circulatory system drugs>Peripheral vasodilators>Tolazoline hydrochloride
Tolazoline hydrochloride
  • Tolazoline hydrochloride

Tolazoline hydrochloride

Price $300
Package 1KG
Min. Order: 1KG
Supply Ability: 10tons
Update Time: 2021-11-02

Product Details

Product Name: Tolazoline hydrochloride CAS No.: 59-97-2
Min. Order: 1KG Purity: 995
Supply Ability: 10tons Release date: 2021/11/02
Chemical PropertiesPale Yellow Crystalline Solid
OriginatorPriscoline,Ciba,US,1948
Usesa-adrenergic antagonist. A peripheral vasodilator
UsesΑn α-adrenergic antagonist. A peripheral vasodilator.
Usesadrenergic blocker
Manufacturing ProcessThe phenyl-acetiminoether hydrochloride of the formula from 12 parts of benzylcyanide and ethanol and HCl is mixed with 8 parts of ethylenediamine hydrate which has been diluted with little alcohol, whereby the crystals go into solution. The whole is then heated on the water-bath until the ammonia odor has disappeared, cooled, concentrated caustic potash solution added, and the separated oil extracted with ether. The solution is dried with potassium carbonate and potassium hydroxide. After evaporation a pale oil is left which distills at 147°C under a pressure of 9 mm and which solidifies in the condenser to a white crystalline mass. The yield amounts to 90% of the theory. The hydrochloride melts at 168° to 170°C.


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