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Postion:Product Catalog >Biochemical Engineering>Polypeptide>Linaclotide
Linaclotide
  • Linaclotide
  • Linaclotide
  • Linaclotide
  • Linaclotide
  • Linaclotide

Linaclotide

Price Get Latest Price
Package 25Kg/Bag
Min. Order: 2Kg/Bag
Supply Ability: 20 tons
Update Time: 2024-04-22

Product Details

Product Name: Linaclotide CAS No.: 851199-59-2
Min. Order: 2Kg/Bag Purity: 98% up
Supply Ability: 20 tons Release date: 2024/04/22

Product Information

Product name

Linaclotide

CAS No.

851199-59-2

Molecular Formula

C59H79N15O21S6

Molecular Weight

1526.736 g/mol

Quality Standard

98% up, Medicine Grade

Appearance

White powder

Sequence

H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH cyclic(1-6),(2-10),(5-13)-tris(disulfide)

COA of Linaclotide

Test

Specifications

Appearance

White or almost white crystalline powder

Identity by HPLC

The reaction is same with the reference substance

Amino Acid Composition

±20% of theoretical

Purity (HPLC)

≥ 98.0%

Related Substance(By HPLC)

Total Impurities(%)≤ 2.0%
Largest Single Impurity(%)≤ 1.0%

Acetate Content(By HPLC)

≤15%

Water Content(By HPLC)

≤5.0%

Bacterial Endotoxins

≤5IU/mg

Usage

Function of Linaclotide


Linaclotide can bind to the guanylate cyclase C-type receptor (GC-C) in the intestinal tract after being taken orally into the human body to increase the intracellular and extracellular cyclic guanylic acid (cGMP) concentration and stimulate the secretion of intestinal juice , To accelerate the migration of the gastrointestinal tract, thereby increasing the frequency of bowel movements. Due to its unique mechanism of action, it is promising to become a therapeutic drug that can not only treat constipation, but also treat abdominal distension, abdominal pain and other clinical symptoms.

Article illustration



Company Profile Introduction

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc.. We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland. Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients. In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA. We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.

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  • Address: Fujian China ,16F, Huicheng Comm. Complex, 839 Xiahe RD.
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