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Postion:Product Catalog >API>Synthetic Anti-infective Drugs>Antifungal Drugs>VORICONAZOLE
VORICONAZOLE
  • VORICONAZOLE

VORICONAZOLE

Price $10
Package 1KG
Min. Order: 10G
Supply Ability: 10MT
Update Time: 2019-01-15

Product Details

Product Name: VORICONAZOLE CAS No.: 137234-62-9
Min. Order: 10G Purity: 99%
Supply Ability: 10MT Release date: 2019/01/15
MF: C16H14F3N5O Appearance: White powder
Usage: Usage: antifungal drug


Chemical name: VORICONAZOLE
MF: C16H14F3N5O
MW: 349.31
CAS: 137234-62-9
Appearance: White powder
Usage: antifungal drug

COA:
 

Product name
Product name

 
Voriconazole
CAS No.
 
137234-62-9 Outer Packing
 
1KG
Production date
 
2016.04.04 Shelf life
 
2018.04.03
Standard adopted
 
USP36
Items of analysis
 
Specification
 
Results
 
Appearance White or almost white crystalline powder white crystalline powder
Identification A.IR B.HPLC Conforms
Impurity C ≤0.2% 0.03%
Impurity D ≤0.1% ND
unknown Impurity ≤0.1% ND
Total impurity ≤0.5% 0.03%
Voriconazole Relatated Compound B ≤0.2% ND
Voriconazole Relatated Compound F ≤0.1% ND
Water ≤0.4% 0.18%
Residue on ignition ≤0.1% 0.06%
Heavy metals ≤10ppm Conforms
Assay(HPLC) 97.5-102% 99.7%
Conclusion
 
Qualified
 


Background:

Voriconazole (vor" i kon' a zole) is a synthetic triazole and a derivative of fluconazole, which is believed to act through inhibition of the fungal 14α-ergosterol demethylase that is responsible for converting lanosterol to ergosterol, which blocks cell membrane synthesis.  Voriconazole has a broad spectrum of activity particularly against candida and aspergillus.  Voriconazole was approved for use in the United States in 2002.  Current indications include treatment of invasive aspergillosis, esophageal candidiasis and serious candidal infections.  It is also used as empiric antifungal therapy in patients with neutropenia and persistent fever as well as preventive antifungal therapy in high risk individuals.  Voriconazole is available as tablets of 50 and 200 mg, in an oral suspension (40 mg/mL) and in a parenteral formulation generically and under the brand name Vfend.  Serious fungal infections are typically treated initially with intravenous voriconazole (4 to 6 mg/kg every 12 hours) for 3 to 10 days, followed by more prolonged therapy with oral forms (20 mg every 12 hours).  Common side effects include nausea, photosensitivity, hallucinations, headache, visual disturbances and rash.

Medical uses:

Voriconazole is used to treat invasive aspergillosis andcandidiasis and fungal infections caused by Scedosporium and Fusarium species, which may occur in immunocompromised patients, including people undergoing allogeneic bone marrow transplant (BMT), who have hematologic cancers or who undergo organ transplants.

It is also used to prevent fungal infection in people as they undergo BMT.

It is also the recommended treatment for the CNS fungal infections transmitted by epidural injection of contaminated steroids.

It can be taken by mouth or given in a doctor's office or clinic by intravenous infusion.

 

Advantages:

 

 

Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.


1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.


2 . Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.


3 . Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate

4 . Warm after-sale service Any of your question would be solved for the first as soon as possible.

VORICONAZOLE 137234-62-9 Pharmaceutical Raw Materials

VORICONAZOLE 137234-62-9 Pharmaceutical Intermediate

VORICONAZOLE 137234-62-9  Raw Chemical Product

VORICONAZOLE 137234-62-9 Supplier & manufactuer

 

Company Profile Introduction

Hubei XinRunde Chemical Co., Ltd covers an area of 95 acres, the proposed construction of the plant will be GMP standards, the factory environment clean and tidy, rational layout, with large and medium-sized production workshop and repocessed shop. It is equipped with advanced equipment quality inspection and research center. Those products of both quality and technical content have reached the domestic advanced level. Products sell well all over the country and exported to Europe and the United States and Southeast Asia,and so on.

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