Product Details
| Product Name:
2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide |
CAS No.:
879085-55-9 |
| Min. Order:
1G |
Purity:
98% |
| Supply Ability:
100KG |
Release date:
2019/07/06 |
AD68
| 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide Basic information |
| Product Name: |
2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide |
| Synonyms: |
2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide;Vismodegib;GDC-0449,Vismodegib;GDC-0449;VisModegib (GDC-0449);BenzaMide, 2-chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(Methylsulfonyl)-;2-Chloro-N-(4-chloro-3-(pyridin-2-yl)-phenyl)-4-(methylsulfonyl)benzamide;VisModegib Base |
| CAS: |
879085-55-9 |
| MF: |
C19H14Cl2N2O3S |
| MW: |
421.303 |
| EINECS: |
1312995-182-4 |
| Product Categories: |
Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API;Inhibitor;Inhibitors |
| Mol File: |
879085-55-9.mol |
 |
| |
| 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide Chemical Properties |
| |
| 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide Usage And Synthesis |
| Chemical Properties |
White Solid |
| Uses |
Targets the Hedgehog (Hh) pathway. Inhibition of the Hh signaling may be effective in the treatment and prevention of many types of human cancers. |
| Uses |
Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM. |
| Definition |
ChEBI: A benzamide obtained by formal condensation between the carboxy group of 2-chloro-4-(methylsulfonyl)benzoic acid and the anilino group of 4-chloro-3-(pyridin-2-yl)aniline. Used for the treatment metastatic basal cell carcinoma. |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
You may like
-
CAS:61379-65-5
$1.00 / 1KG
-
CAS: 121219-25-8
$7.00 / 1KG
-
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$0.00/1g |
VIP3Y
|
Senova Technology Co. Ltd.
|
2023-12-14 |
|
|
$73.00/5mg |
|
Qiuxian Baitai New Material Co., LTD
|
2021-12-21 |
|
|
$15.00/1KG |
|
Zhuozhou Wenxi import and Export Co., Ltd
|
2021-06-26 |
![2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide](https://img.chemicalbook.com/ProductImageEN/2018-8/Large/eb8973f2-5ca7-4bed-b62a-db84add1c6cc.jpg)
![2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide](https://img.chemicalbook.com/ProductImageEN/2018-8/Small/eb8973f2-5ca7-4bed-b62a-db84add1c6cc.jpg)
China