Testosterone

Price	$1
Package	1KG

Product Details

Product Name: Testosterone	CAS No.: 58-22-0
Min. Order: 1G	Purity: 98%
Supply Ability: 100KG	Release date: 2019/07/06

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Testosterone Basic information

Chemical Properties Indications and Uses Pharmacokinetics Application in Particular Diseases

Product Name:	Testosterone
Synonyms:	testred;TESTOSTERONE;testex;testoderm;TESTOSTERON;ORQUISTERON;oreton;PRIMOTESTON
CAS:	58-22-0
MF:	C19H28O2
MW:	288.42
EINECS:	200-370-5
Product Categories:	MI;TPI;Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Intracellular receptor;Steroid and Hormone;API;testosterone;TESTIM;Inhibitors;4-CPRC ada@tuskwei.com whatsapp;8618031153937
Mol File:	58-22-0.mol

Testosterone Chemical Properties

Melting point	152-156 °C
alpha	101 º (c=1, dioxane 25 ºC)
Boiling point	370.65°C (rough estimate)
density	1.0484 (rough estimate)
refractive index	1.4709 (estimate)
Fp	5 °C
storage temp.	2-8°C
solubility	45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble18.2 mg/ml
Merck	13,9255
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference	58-22-0(CAS DataBase Reference)
NIST Chemistry Reference	Testosterone(58-22-0)
EPA Substance Registry System	Androst-4-en-3-one, 17-hydroxy-, (17.beta.)-(58-22-0)

Safety Information

Hazard Codes	T,Xn,F
Risk Statements	60-61-11-19-20-40-63-45-36-20/21/22-38
Safety Statements	53-45-24/25-36/37-26-16
RIDADR	UN 2252 3/PG 2
WGK Germany	3
RTECS	XA3030000
Hazardous Substances Data	58-22-0(Hazardous Substances Data)

Testosterone Usage And Synthesis

Chemical Properties	White crystalline powder with no aroma. Its melting point is 155℃, specific rotary power is [α]24D+109° (4%, ethanol), and its ethanol solution has the greatest absorbance at a wavelength of 240nm. It is easily soluble in ethanol (1:5), soluble in ether (1:100), and insoluble in water. LD50 (Large mice, venal transfusion) 326mg/kg. Studies show that it has latent carcinogenic effects on test animals.
Indications and Uses	Testosterone is the main natural male sex hormone in mammals and is a steroid hormone with 19 carbon atoms. It is the main male sex hormone secreted by the testes, and it is also the most active male sex hormone. It promotes humans’ and animals’ sex organ and secondary sex characteristic development, sperm maturation, and protein metabolism for muscle strengthening. Testosterone controls the growth and development of male sex organs and male secondary sex characteristics. It is mainly used in replacement therapy for eunuchism, treatment for male menopause syndrome, and treatment for impotence, and it is also used in biochemical research.
Pharmacokinetics	Testosterone can bind non-specifically with plasma albumins in blood, and it can also bind with plasma sex hormone binding globulins. It can be converted into estradiol and estrone in peripheral tissue. Testosterone is mostly degraded in the liver, where its A-ring is restored, and it is converted into 17- ketosteroid under the effects of 17β-Hydroxysteroid dehydrogenase. Along with androsterone, epiandrosterone, and etiocholanlone, it is combined with glucuronic acid or sulfate and excreted in urine. Most metabolites in urine that are excreted by binding to glucuronic acid belong to 17-ketosteroids.
Application in Particular Diseases	In Osteoporosis: Testosterone replacement is not FDA approved for the prevention or treatment of osteoporosis. It should not be used solely for these indications but might be beneficial to reduce bone loss in patients needing therapy for hypogonadal symptoms. In a few studies, women receiving oral methyltestosterone 1.25 or 2.5 mg daily or testosterone implants 50 mg every 3 months had increased BMD. Various salt forms of testosterone were associated with increased BMD in some studies of hypogonadal men or senior men with normal hormone levels or mild hormonal deficiency. Transdermal gel, oral, intramuscular, and pellet testosterone products are available. Patients using them should be evaluated within 1 to 2 months of initiation and then every 3 to 6 months thereafter.
Chemical Properties	white crystalline odourless solid
Uses	Secreted by the testis and is converted to dihydrotestosterone in the target tissue where is appears to mediate many of the biological actions of testosterone. CONTROLLED SUBSTANC
Uses	Testosterone secreted by the testis is converted to dihydrotestosterone in the target tissues where it appears to mediate many of the biological actions of testosterone. Androgens direct the development of the male phenotype during embryogenesis and at puberty.
Uses	androgen, antineoplastic
Uses	Testosterone, Principal hormone of the testes, produced by the interstitial cells. Major circulating androgen; converted by 5α-reductase in androgen-dependent target tissues to 5α-dehydrotestosterone which is required for normal male sexual differentiation. Also converted by aromatization to Estradiol. Testerone is a controlled substance (anabolic steroid). Androgen.
Uses	Rivastigmine metabolite
Definition	ChEBI: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-41C-5..
Biological Activity	Endogenous androgen receptor agonist.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates： Pharmaceutical intermediates; OLED intermediates;

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