Product Details
| Product Name:
Cinobufagin |
CAS No.:
470-37-1 |
| Min. Order:
1g |
Purity:
99% |
| Supply Ability:
100KG |
Release date:
2019/07/06 |
| Cinobufagin Basic information |
| Description References |
| Product Name: |
Cinobufagin |
| Synonyms: |
RARECHEM BK HC T302;TRANS-3-PHENYLPROPENOIC ACID;TRANS-3-BENZENEPROPENOIC ACID;TRANS-CINNAMYLIC ACID;16-beta)-bet;22-dienolide,16-(acetyloxy)-14,15-epoxy-3-hydroxy-,(3-beta,5-beta,15-bufa-2;cinobufagine;AKOS B004228 |
| CAS: |
470-37-1 |
| MF: |
C26H34O6 |
| MW: |
442.55 |
| EINECS: |
205-398-1 |
| Product Categories: |
Steroids;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract |
| Mol File: |
470-37-1.mol |
 |
| |
| Cinobufagin Chemical Properties |
| Melting point |
133 °C(lit.) |
| Boiling point |
300 °C(lit.) |
| Fp |
>230 °F |
| storage temp. |
2-8°C |
| Hazard Codes |
Xi,T+,Xn |
| Risk Statements |
36/37/38-26/27/28-42/43-20/22 |
| Safety Statements |
26-36-45-36/37/39-22-24/25 |
| RIDADR |
UN 2811 6.1/PG 1 |
| WGK Germany |
3 |
| RTECS |
GD7850000 |
| HazardClass |
6.1(a) |
| PackingGroup |
II |
| HS Code |
29322090 |
| Provider |
Language |
| SigmaAldrich |
English |
| ACROS |
English |
| ALFA |
English |
| |
| Cinobufagin Usage And Synthesis |
| Description |
Cinobufagin is a cardiotoxic bufanolide steroid secreted by the Asiatic toad Bufo gargarizans, having similar effects to digitalis and used in traditional Chinese medicine. It has potential antineoplastic activity and now is widely used in clinical practice, especially in anti-liver cancer. It has benn found to suppress cancer cell proliferation and cause apoptosis in cancer cells via a sequence of apoptotic modulators, including mitochondrial Bax and cytosolic chromosome c, and caspases 3, 8, and 9. |
| References |
1. https://en.wikipedia.org/wiki/Cinobufagin
2. https://www.cancer.gov/publications/dictionaries/cancer-drug?cdrid=689412
3. http://www.yourdictionary.com/cinobufagin
4. https://www.medchemexpress.com/cinobufagin.html |
| Uses |
Cinobufagine is a major component of cinobufacini (huachansu), is an important cardenolidal steroid. Cinobufagine was show |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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