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Postion:Product Catalog >API>Synthetic Anti-infective Drugs>Antifungal Drugs>Butoconazole
Butoconazole
  • Butoconazole

Butoconazole

Price $1 $2
Package 1KG 1KG
Min. Order: 1KG
Supply Ability: 200kg
Update Time: 2019-09-02

Product Details

Product Name: Butoconazole CAS No.: 64872-76-0
Min. Order: 1KG Purity: 98%
Supply Ability: 200kg Release date: 2019/09/02
Product No:: Cindy 42
Product Name:
Butoconazole
Synonyms:
BUTOCONAZOLE;Butooonazole;BUTONAZOLE;1-[4-(4-Chlorophenyl)-2-(2,6-dichlorophenyl)sulfanyl-butyl]imidazole;(±)-1-[4-(4-Chlorophenyl)-2-[(2,6-dichlorophenyl)thio]butyl]-1H-imidazole;1-[2-[(2,6-Dichlorophenyl)thio]-4-(4-chlorophenyl)butyl]-1H-imidazole
CAS:
64872-76-0
MF:
C19H17Cl3N2S
MW:
411.78
EINECS:
 
Product Categories:
VIDAZA
Mol File:
64872-76-0.mol
Article illustration
 
Butoconazole Chemical Properties
Melting point 
68-70.5°
CAS DataBase Reference
64872-76-0(CAS DataBase Reference)
 
Safety Information
MSDS Information
 
 
Butoconazole Usage And Synthesis
Uses
antineoplastic, pyrimidine antimetabolite
Definition
ChEBI: A member of the class of imidazoles that is 1H-imidazole in which the hydrogen attached to the nitrogen is substituted by a 4-(4-chlorophenyl)-2-[(2,6-dichlorophenyl)sulfanyl]butyl group. An antifungal agent, it is used as its nitrate sa t in gynaecology for treatment of vulvovaginal infections caused by Candida species, particularly Candida albicans.
Brand name
Femstat (Roche);Femstat 3 (Bayer); Gynazole-1 (KV Pharmaceutical).
Enzyme inhibitor
This fungicide (FW = 411.78 g/mol; CAS 64872-77-1), also known as Femstat?, Femstat-3?, Gynazole-1?, and systematically as 1-[4- (4- chlorophenyl) -2-[ (2,6-dichlorophenyl) -sulfanyl]butyl]-1H-imidazole (* = chiral center), is believed to inhibit steroid synthesis, targeting the conversion of lanosterol to ergosterol and modifying membrane composition/function. At 80 μM, butoconazole was strictly fungistatic against early stationary-phase Candida albicans cells. During early log- phase growth, butoconazole were highly lethal at 20 μM. In 1995, butoconazole was approved for treatment of vaginal yeast infections.
 
Butoconazole Preparation Products And Raw materials
Raw materials
tert-Butanol-->4-Chlorobenzyl chloride-->2,6-DICHLOROTHIOPHENOL
 

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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