Enalaprilat
| Price | $1 |
| Package | 25Kg/Drum |
| Min. Order: | 25Kg/Drum |
| Supply Ability: | 1ton |
| Update Time: | 2019-10-30 |
Product Details
| Product Name: Enalaprilat | CAS No.: 76420-72-9 |
| Min. Order: 25Kg/Drum | Purity: >95% |
| Supply Ability: 1ton | Release date: 2019/10/30 |
Brief Description
Prodcut name
Enalaprilat
Synonyms
MOQ
1KG
CAS No.
- 76420-72-9
Appearance
white to off-white
Molecular Formula
C18H24N2O5
Molecular Weight
348.39
Assay
99%
Application
Pharma grade or research purpose
Packing
As per your request
Storage
Preserve in tight, light-resistant containers in a cool place
Remarks
NA
Custom synthesis
Available
Medical use
Enalaprilat is the active metabolite of enalapril. It is the first dicarboxylate-containing ACE inhibitor and was developed partly to overcome these limitations of captopril. The sulfhydryl-moiety was replaced by a carboxylate-moiety, but additional modifications were required in its structure-based design to achieve a potency similar to captopril.
Enalaprilat, however, had a problem of its own. The consequence of the structural modifications was to give it ionisation characteristics that do not allow sufficient GI absorption for oral administration (in tablets). Thus, enalaprilat was only suitable for intravenousadministration. This was overcome by the esterification of enalaprilat with ethanol to produce enalapril.
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China- Since: 2012-02-03
- Address: No. 7, No. 7, No. 1, No. 160, Qiaokou Road, Qiaokou District, Qiaokou city.