Collagenase NEW

Functions and effects of collagen: 

(1) Collagen plays an important role in the process of wound healing and scar formation. It can not only serve as the premise of elastic tissue and adhesive substances, but also stimulate cell development and differentiation, stimulate tissue differentiation and proliferation, and stimulate connective tissue differentiation and proliferation. It can also stimulate capillary neovascularization and chemotaxis monocytes and fibroblasts. It also has the function of nutrition and regulation of granulation tissue. It has been reported that the treatment of skin ulcers caused by different reasons with collagen has a good effect, can make the surface and deep ulcer epithelization, conducive to the formation of granulation tissue. 

(2) 70%-80% of organic matter in bone is collagen, and when bone is formed, sufficient collagen fibers must first be synthesized to form the skeleton of bone. Therefore, some people call collagen the bone of bones. Collagen fiber has strong toughness and elasticity, if a long bone is compared to a cement column, then collagen fiber is the steel frame of the column, and the lack of collagen, just like the use of inferior steel in the building, the risk of breaking is very dangerous. 

(3) The role of collagen in breast enhancement has long been well known. The breast is mainly composed of connective tissue and adipose tissue, and the tall and plump breast largely relies on the support of connective tissue. Collagen is the main component of connective tissue. "In connective tissue, collagen is often interwoven with and polyglycoprotein into a network structure, producing a certain mechanical strength, which is the material basis for supporting the curve of the human body and reflecting the tall and straight body." 

(4) Collagen is known as "bone in bone, skin in skin, meat in meat", can be said to be a powerful backing of the dermis, its role in the skin is self-evident. Protection, with appropriate flexibility: Under the epidermis, the dermis occupies most of the structure, with a thickness of about 2 mm. It can be divided into three layers, namely the papillary layer, the subpapillary layer and the reticular layer, etc. Most of the proteins are composed of collagen and elastin, while the others are nerves, capillaries, sweat glands and sebaceous glands, lymphatic vessels and hair roots. 70% of the skin is composed of collagen. The skin is like a big jacket tightly wrapped around the body, with a large surface area. When the limbs are moved, the collagen in the skin plays its function, making the skin have a protective function, but also have appropriate elasticity and hardness.

Collagen: Collagen is also known as collagen. A fibrous protein consisting of three peptide chains twisted into a spiral shape. It exists in the body in the form of collagen fibers, which dissolve into glue when heated in water. It is abundant in higher animals, accounting for about 1/3 of the total protein. It is mainly distributed in connective tissues, such as 70% of the dry weight of skin is collagen. Collagen is a glycoprotein that contains sugar and a large amount of glycine, proline and hydroxyproline, but does not contain cystine or tryptophan. It is an incomplete protein with low nutritional value, but it is very important for the formation of skin, blood vessels, bones, tendons, teeth and cartilage in animals and humans, and is the main matrix of these connective tissues. 

If the biosynthesis of collagen is abnormal, or the collagen changes abnormally for other reasons, it may lead to collagen disease. In clinical medicine, the occurrence of collagen diseases such as rheumatoid arthritis and lupus erythematosus is related to abnormal collagen metabolism. In industry, skin and bone can be used as raw materials to prepare impure collagen, such as cow skin glue, fish glue and bone glue and other industrial glue for bonding. Ejiao made from donkey skin is an important tonic medicine and has the function of tonifying blood. White gelatin (also known as gelatin) is a pure collagen protein, which is generally made of skin and bone as raw materials, after acid hydrolysis, and then extracted with water at 60℃. Gelatin can be eaten or used to make photographic latex, and can also be used to extract hydroxyproline.