CROSCARMELLOSE SODIUM

Product Specification

Technical Specifications:

CAS Number:74811-65-7

Molecular Formula: C₈H₁₆O₈

Molecular Weight: 240.21

Melting Point: 1710?? C

Boiling Point: 2230

Solubility: Practically insoluble in acetone, in anhydrous ethanol and in toluene.Synonyms: CARBOXYMETHYL CELLULOSE Carboxymethylcellulose Cellulose, carboxymethyl ether

 Introduction of product:

Sodium croscarmellose is an internally cross-linked sodium carboxymethylcellulose for use as a super disintegrant in pharmaceutical formulations. E468 is the E number of crosslinked sodium carboxymethyl cellulose, used in food as an emulsifier. Croscarmellose sodium, or sodium CMC, is a cross-linked polymer of carboxymethylcellulose sodium. It appears as white, fibrous, free-flowing powder, and is used commonly as an FDA-approved disintegrant in pharmaceutical manufacturing. Disintegrants facilitate the breakup of a tablet in the intestinal tract after oral administration. Cross-linking allows enhanced bioavailability of the drug through superior drug dissolution. Without a disintegrant, tablets may not dissolve appropriately and may effect the amount of active ingredient absorbed, thereby decreasing effectiveness.