Polymyxin B sulfate NEW

Price	$5	$0.1
Package	1KG	1000KG

Min. Order:	1KG
Supply Ability:	g-kg-tons, free sample is available
Update Time:	2024-04-08

Product Details

Product Name: Polymyxin B sulfate	CAS No.: 1405-20-5
Min. Order: 1KG	Purity: 98%
Supply Ability: g-kg-tons, free sample is available	Release date: 2024/04/08
Lead time: In stock, ready for shipment	Packaging: bag/bottle/drum/IBC
Delivery: By express, by air, by sea	Origin: Manufacturer, advantage product
COA, MSDS: Available, contact us for details	Name: Tina

1. Materials information

Name	Polymyxin B sulfate
Synonym	More Synonyms

Description	Polymyxin B Sulfate is a cationic surfactant antibiotic agent. A mixture of polymyxins B1 and B2, increases the permeability of the cell membrane.In vitro: RB50 is resistant to killing by polymyxin B at concentrations up to 100 μg/ml.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Others
References	[1]. Rolin O et al. Enzymatic modification of lipid A by ArnT protects Bordetella bronchiseptica against cationic peptides and is required for transmission. Infect Immun. 2014 Feb;82(2):491-9. [2]. Pye CC et al. Evaluation of biofilm production by Pseudomonas aeruginosa from canine ears and the impact of biofilm on antimicrobial susceptibility in vitro.Vet Dermatol. 2013 Aug;24(4):446-9

Description

Polymyxin B Sulfate is a cationic surfactant antibiotic agent. A mixture of polymyxins B1 and B2, increases the permeability of the cell membrane.In vitro: RB50 is resistant to killing by polymyxin B at concentrations up to 100 μg/ml.

Related Catalog

Signaling Pathways >> Anti-infection >> Bacterial

Research Areas >> Others

References

[1]. Rolin O et al. Enzymatic modification of lipid A by ArnT protects Bordetella bronchiseptica against cationic peptides and is required for transmission. Infect Immun. 2014 Feb;82(2):491-9.

[2]. Pye CC et al. Evaluation of biofilm production by Pseudomonas aeruginosa from canine ears and the impact of biofilm on antimicrobial susceptibility in vitro.Vet Dermatol. 2013 Aug;24(4):446-9

Boiling Point	1651ºC at 760 mmHg
Melting Point	217-220°C (dec.)
Molecular Formula	C55H96N16O13.H2SO4(PolymyxinB2Sulfate)
Molecular Weight	1287.53 (PolymyxinB2Sulfate)
Flash Point	952.3ºC
PSA	573.64000
LogP	2.54990
Appearance of Characters	powder
Vapour Pressure	0mmHg at 25°C
Storage condition	2-8°C
Water Solubility	H2O: 50 mg/mL

Polymyxin B Sulfate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TR1150000

CHEMICAL NAME :
Polymyxin B sulfate

CAS REGISTRY NUMBER :
1405-20-5

LAST UPDATED :
199504

DATA ITEMS CITED :
13

MOLECULAR FORMULA :
C43-H82-N16-O12.xH2-O4-S

MOLECULAR WEIGHT :
1701.97

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Oral

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
790 mg(base)/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Intraperitoneal

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
20500 ug(base)/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Subcutaneous

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
59500 ug(base)/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Intravenous

SPECIES OBSERVED :
Rodent - mouse

DOSE/DURATION :
5400 ug(base)/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :
Intravenous

SPECIES OBSERVED :
Mammal - dog

DOSE/DURATION :
8 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :
LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :
Intracerebral

SPECIES OBSERVED :
Mammal - dog

DOSE/DURATION :
320 ug/kg

TOXIC EFFECTS :
Behavioral - coma

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :
Subcutaneous

SPECIES OBSERVED :
Rodent - guinea pig

DOSE/DURATION :
58 mg/kg

TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified

TEST SYSTEM :
Yeast - Saccharomyces cerevisiae

DOSE/DURATION :
5 mg/L

REFERENCE :
AMACCQ Antimicrobial Agents and Chemotherapy. (American Soc. for Microbiology, 1913 I St., NW, Washington, DC 20006) V.1- 1972- Volume(issue)/page/year: 2,36,1972 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81938 No. of Facilities: 152 (estimated) No. of Industries: 4 No. of Occupations: 6 No. of Employees: 967 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9499 No. of Facilities: 383 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1149 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81938 No. of Facilities: 1842 (estimated) No. of Industries: 19 No. of Occupations: 18 No. of Employees: 173376 (estimated) No. of Female Employees: 145041 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Precautionary Statements	P301 + P312 + P330
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
Safety Phrases	S22-S24/25
RIDADR	3249
WGK Germany	3
RTECS	TR1150000
Packaging Group	III
Hazard Class	6.1(b)

2. Packaging of materials

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.

Or smaller package 1kg/bottle, 10kgs/bottle as request.

Article illustration

3. Shipping & Delivery

By Express

Provide door to door service

Suitable for goods under 50kg

Delivery: 3-7 days

Cost: low cost

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By Air

Provide airport to airport service

Suitable for goods over 50kg

Delivery: 3-14 days

Cost: high cost

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By Sea

Provide seaport to seaport service

Suitable for goods over 100kg

Delivery: 2-45 days

Cost: low cost

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4. Contact information

For more details, pls contact us freely.

Email address: Tina@fdachem.com

Mob: 86 15225627621

WhatsApp/Skype/Wechat/LINE: 86 15225627621

Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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