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ChemicalBook >>Riluzole>>6-(Trifluoromethoxy)-1,3-benzothiazol-2-amine(1744-22-5)

6-(Trifluoromethoxy)-1,3-benzothiazol-2-amine(1744-22-5)

6-(Trifluoromethoxy)-1,3-benzothiazol-2-amine(1744-22-5)
Product IdentificationBack to Contents
【Product Name】

6-(Trifluoromethoxy)-1,3-benzothiazol-2-amine
【Synonyms】

2-Amino-6-trifluoromethoxybenzothiazole
2-Benzothiazolamine, 6-(trifluoromethoxy)-
6-(Trifluoromethoxy)-2-aminobenzothiazole
Benzothiazole, 2-amino-6-trifluoromethoxy-
Rilutek
【CAS】

1744-22-5
【Formula】

C8H5F3N2OS
【Molecular Weight】

234.2
【RTECS】

DL2830000
【Merck】

12,8389
Physical and Chemical PropertiesBack to Contents
【Appearance】

Powder.
【Solubility in water】

Insoluble
【Melting Point】

117
【Boiling Point】

296
【Vapor Pressure】

0.0015 (25 C)
【Density】

1.572 g/cm3 (20 C)
【pKa/pKb】

10.45 (pKb)
【Partition Coefficient】

2.84
【Heat Of Vaporization】

53.6 kJ/mol
【Usage】

Used to treat amyotrophic lateral sclerosis.
First Aid MeasuresBack to Contents
【Ingestion】

Do not induce vomiting without medical advice.
【Inhalation】

Move to fresh air. Call a physician immediately.
【Skin】

Rinse immediately with plenty of water and seek medical advice.
【Eyes】

In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Handling and StorageBack to Contents
【Storage】

Store at room temperature in a tightly sealed container.
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

PVC or other plastic gloves. Protective work clothing. Safety glasses with side-shields.
【Exposure Effects】

Chronic toxicity: Chronic exposure may cause nausea and vomiting, higher exposure causes unconsciousness. Local effects: Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting. Specific effects: May include moderate to severe erythema (redness) and moderate edema (raised skin), nausea, vomiting, headache.
Fire Fighting MeasuresBack to Contents
【Flash Point】

133
【Fire Fighting】

Extinguish using dry chemical, CO2, water spray or alcohol foam. Wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. Water mist may be used to cool closed containers.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Eliminate all ignition sources. Absorb and/or contain spill with inert materials (e.g., sand, vermiculite). Then place in appropriate container. For large spills, use water spray to disperse vapors, flush spill area. Prevent runoff from entering waterways or sewers.
Stability and ReactivityBack to Contents
【Incompatibilities】

Oxidizing and spontaneously flammable products.
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