Product Identification | Back to Contents | 【Product Name】
N-(1-Methylethyl)-4-((2-methylhydrazino)methyl)benzamide | 【Synonyms】
4-((2-Methylhydrazino)methyl)-n-Isopropylbenzamide Ibenzmethyzin n-(1-Methylethyl)-4 n-4-isopropylcarbamoylbenzyl-n'-methylhydrazine n-Isopropyl-alpha-(2-methylhydrazino)-p-toluamide p-(N'-Methylhydrazinomethyl)-n-Isopropylbenzamide | 【CAS】
671-16-9 | 【Formula】
C12H19N3O | 【Molecular Weight】
221.3 | 【EINECS】
211-582-2 | 【RTECS】
XS4550000 | 【RTECS Class】
Tumorigen; Drug; Mutagen; Reproductive Effector | 【Merck】
12,7938 | 【Beilstein/Gmelin】
958270 |
First Aid Measures | Back to Contents | 【Ingestion】
Seek medical attention. If individual is drowsy or unconscious, do not give anything by mouth; place individual on the left side with the head down. Contact a physician, medical facility, or poison control center for advice about whether to induce vomiting. If possible, do not leave individual unattended. | 【Inhalation】
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention. | 【Skin】
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. | 【Eyes】
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention. |
Handling and Storage | Back to Contents | 【Storage】
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage. | 【Handling】
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood. |
Hazards Identification | Back to Contents | 【Inhalation】
Interstitial pneumonitis occurs rarely and may be an allergic reaction during therapeutic use. | 【Skin】
Pruritus, hyperpigmentation, flushing, alopecia, and jaundice may be noted. Herpetic lesions may occur. | 【Eyes】
Nystagmus, diplopia, papilledema, photophobia and retinal hemorrhage may occur with therapeutic use. | 【Ingestion】
Ausea, vomiting and diarrhea may occur. |
Exposure Controls/Personal Protection | Back to Contents | 【Personal Protection】
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots. | 【Respirators】
Respiratory protection should be an adjunct to and not a substitute for engineering controls.<BR>Organic vapor acid gas canister; done in the open, an area away from drafts and traffic | 【Exposure Effects】
Procarbazine is a weak mao inhibitor. A hypertensive reaction may occur with concurrent use of sympathomimetic agents, tricyclic antidepressants, and foods with high tyramine content; these reactions are poorly documented. with therapeutic use - paresthesias, neuropathies, dizziness, headache, insomnia, frequent nightmares, nervousness, depression, hallucinations, seizures, coma and tremors have been reported. Procarbazine is not recommended for use during pregnancy or lactation. |
Fire Fighting Measures | Back to Contents | 【Fire Fighting】
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire. |
Accidental Release Measures | Back to Contents | 【Small spills/leaks】
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces. |
Stability and Reactivity | Back to Contents | 【Stability】
Stable in light, slowly oxidized in air. Hydrochloride stable @ room temperature (in presence of oxygen, oxidn is accelerated by incr temperature). | 【Incompatibilities】
Strong oxidizing agents. |
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Company Name: |
T&W GROUP |
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021-61551611 13296011611 |
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+86 21-50676805 |
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Eastbang Pharmaceuticals Technology Co., Ltd. |
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