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Salicylamide(65-45-2)

Salicylamide(65-45-2)
Product IdentificationBack to Contents
【Product Name】

Salicylamide
【Synonyms】

2-Carboxamidophenol
2H-Pyran-2-acetic acid, alpha-ethyl-6-(5-(2-(5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro(4.1.5.3)pentadec-13-en-9-yl)-2-hydroxy-1,3-dimethyl-4-oxoheptyl)tetrahydro-3,5-dimethyl-
2-Hydroxybenzamide
A-28086A
Algamon
Antibiotic A 28086 factor A
Antibiotic A 28086A
Antibiotic C 7819B
C-7819B
Oramid
Salicylic acid amide
Urtosal
【CAS】

55134-13-9
【CAS】

65-45-2
【Formula】

C43H72O11
【Formula】

C7H7NO2
【Molecular Weight】

765.04
【Molecular Weight】

137.13999999999999
【EINECS】

200-609-3
【RTECS】

VN6475000
【RTECS】

VO8640000
【RTECS Class】

Drug; Reproductive Effector; Primary Irritant
【Merck】

12,6506
【Merck】

12,8480
【Beilstein/Gmelin】

1678311
【Beilstein/Gmelin】

742439
【Beilstein Reference】

4-10-00-00169
Physical and Chemical PropertiesBack to Contents
【Appearance】

White or slightly pink crystalline powder.
【Solubility in water】

2 g/L (20 C)
【Melting Point】

137
【Boiling Point】

318
【Vapor Pressure】

0.0002 (25 C)
【Density】

1.33 g/cm3 (20 C)
【pKa/pKb】

8.37 (pKa)
【Partition Coefficient】

1.28
【Heat Of Vaporization】

58.2 kJ/mol
【Heat Of Combustion】

-3352 kJ/mol
【Usage】

Antibiotic.
【Usage】

Medication.
【Refractive Index】

1.562 (20 C)
First Aid MeasuresBack to Contents
【Ingestion】

If swallowed, wash out mouth with water provided person is conscious. Call a physician.
【Ingestion】

If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
【Ingestion】

May be fatal if swallowed.
【Inhalation】

May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
【Inhalation】

If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
【Inhalation】

Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
【Skin】

May cause skin irritation. May be harmful if absorbed through the skin.
【Skin】

Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
【Skin】

In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
【Eyes】

May cause irritation.
【Eyes】

Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
【Eyes】

In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
Handling and StorageBack to Contents
【Storage】

Store at 2 - 8 C. Keep container tightly closed.
【Storage】

Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
【Handling】

Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Hazards IdentificationBack to Contents
【Inhalation】

Inhalation of dust may cause respiratory tract irritation.
【Skin】

May cause skin irritation.
【Eyes】

Causes eye irritation.
【Ingestion】

May cause irritation of the digestive tract. Overexposure may produce CNS depression, hypotension, eventually respiratory arrest, but does not produce excitement, seizures, acidosis, or hypoprothrombinemia. May be harmful if swallowed.
【Hazards】

Emits toxic fumes under fire conditions.
【EC Risk Phrase】

R 22 36/37/38
【EC Risk Phrase】

28
【EC Safety Phrase】

28 36/37 45
【EC Safety Phrase】

S 22 26 36/37/39
【UN (DOT)】

2811
Exposure Controls/Personal ProtectionBack to Contents
【Personal Protection】

Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
【Personal Protection】

Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
【Respirators】

Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
【Respirators】

Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection,
【Exposure Effects】

studies with animals indicate that salicylamide overdoses may produce central nervous system depression (rather than CNS stimulation sometimes seen early in salicylate poisonings.)
【Exposure Effects】

Target organs: heart, skeletal muscles.
【Poison Class】

3
Fire Fighting MeasuresBack to Contents
【Flash Point】

146
【Fire Fighting】

Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
【Fire Fighting】

Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
【Fire Potential】

This material is probably combustible.
Accidental Release MeasuresBack to Contents
【Small spills/leaks】

Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
【Small spills/leaks】

Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability and ReactivityBack to Contents
【Incompatibilities】

Acids (mineral, non-oxidizing, e.g. hydrochloric acid, hydrofluoric acid, muriatic acid, phosphoric acid), acids (mineral, oxidizing, e.g. chromic acid, hypochlorous acid, nitric acid, sulfuric acid), metals (alkali and alkaline, e.g. cesium, potassium, sodium), metals and metal compounds (toxic, e.g. beryllium, lead acetate, nickel carbonyl, tetraethyl lead), oxidizing agents (strong, e.g. bromine, hydrogen peroxide, nitrogen dioxide, potassium nitrate), reducing agents (strong, e.g. aluminum carbide, chlorosilane, hydrogen phosphide, lithium hydride), water reactive substances (e.g. acetic anyhdride, alkyl aluminum chloride, calcium carbide, ethyl dichlorosilane).
【Stability】

Stable if stored as directed.
【Stability】

Stable under normal temperatures and pressures. May discolor on exposure to light.
【Incompatibilities】

Strong oxidizing agents.
【Decomposition】

Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
【Decomposition】

Oxides of carbon.
Transport InformationBack to Contents
【UN Number】

2811
【Hazard Class】

6.1
【Packing Group】

II
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