别名
Cyclohexylcarbamic acid 3´-carbamoyl-biphenyl-3-yl ester
一般描述
URB597 binds to active sites of fatty acid amide hydrolases and inhibits their activity. URB597 alters expression of tyrosine hydroxylase and interacts with abnormal-cannabidiol (Abn-CBD) and peroxisome proliferator-activated receptors (PPARs). URB597 elicits antinociception property via cannabinoid receptor by maintaining endocannabinoid anandamide (AEA) levels. URB597 reduces abnormal hyperactivity in neurons and could be for treatment of seizures and improving synaptic plasticity.
生化/生理作用
Potent, selective fatty acid amide hydrolase (FAAH) inhibitor.
制备说明
URB597 is soluble in DMSO at a concentration that is approximately 14 mg/ml.
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司
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