中文名:塞马西尼
英文名:SU5416
中文别名:1,3-二氢-3-[(3,5-二甲基-1H-吡咯-2-基)亚甲基]-2H-吲哚-2-酮
英文别名:Semaxanib|Semaxinib|SU5416|204005-46-9|SU 5416|194413-58-6|SU-5416|Semoxind|Semaxanib (SU5416)|(Z)-3-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)indolin-2-one|TSU 16|NSC-696819|VEGFR2 Kinase Inhibitor III|(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1H-i
纯度:≥98% (HPLC)
货号:S125835
包装:10mg、50mg、250mg
Cas号:204005-46-9
存储温度:-20°C储存
产品介绍:
Semaxanib (SU5416)是VEGFR(Flk-1/KDR)抑制剂,IC50为1.23 μM,比对PDGFRβ的抑制性高20倍,对EGFR,InsR和FGFR无活性。It was used to study the mechanism of development of cerebral vasculature in zebrafish hindbrain,and study the pulmonary vascular remodeling in response to hypoxia in mouse model of pulmonary arterial hypertension.
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