西力士
中文同义词: 他达那非;他地那非;(6R-12aR)-6-(1,3-苯并二噁茂-5-基)-2-甲基-2,3,6,7,12,12a-六氢化吡嗪并[1',2'-1,6]-吡啶并[3,4-b]吲哚-1,4-二酮;(6R-12AR)-6-(1,3-苯并二茂-5-基)-2-甲基-2,3,6,7,12,12A-六氢化吡嗪并[1',2'-1,6]-吡啶并[3,4-B]吲哚-1,4-二酮
英文名称: Tadalafil
英文同义词:(6r,12ar)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione;Cialis
CAS号: 171596-29-5
分子式: C22H19N3O4
分子量: 389.4
EINECS号: 200-835-2
用途：磷酸二酯酶5抑制剂,于治疗男性勃起功能障碍，第二代磷酸二酯酶5抑制剂,用于治疗男性bo起功能障碍。
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他达那非用途
他达那非溶解性
他达那非副作用
他达那非别名西力士
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Tadalafil (Cialis)
Synonyms:(6r,12ar)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
CAS:171596-29-5
MF:C22H19N3O4
MW:389.4
EINECS:200-835-2
hemical Properties:White to off-white cyrstalline solid
Assay:99%
MP: 298-300°C
Uses:It is a kind of PDE-5 inhibitors which can be used for the treatment of male erectile dysfunction. It is also the second generation of phosphodiesterase type 5 inhibitors used to treat male erectile dysfunction.
Drug For Treatment of Male Erectile Dysfunction Disease:
Cialis is tadalafil, is an orally administrated drug developed by the pharmaceutical company Eli Lily for treatment of male erectile dysfunction disease. It belongs to the second generation of phosphodiesterase type 5 inhibitors. Study has shown that compared with sildenafil, the onset rate of Cialis is very rapid with about 15 ~ 20 min for onset and with long-term effects up to 36h. Its T1/2 was 17.5h. In a study including 348 cases of patients with mild to severe erectile dysfunction, male patients were randomized for being subject to 20 mg of tadalafil or placebo. The results have showed that, compared with placebo, the intercourse success rate at 24 and 36 hours after taking the drug are both improved with most male patients can successfully have sexual intercourse for twice within 36 hours. There is also no difference in the incidence and severity of the adverse drug reactions compared with placebo. In the tadalafil group, more than 5% of men get headache and indigestion.
[Adverse reactions] it has no serious adverse reactions. No adverse reactions such as facial flushing, vision abnormalities after serving have been observed. There has been occasionally headache and indigestion.
[Note] for patients serving nitrates, angina, heart disease, uncontrolled hypertension or hypotension. Patients who had got stroke within the past six months should be disabled.
Items Enterprise Result
Description Off-white or white crystalline powder white crystalline powder
Identification IR\HPLC Conform to standard
Loss on drying ≤0.5% 0.1%
Residue on ignition ≤0.1% 0.03%
Heavy metals ≤0.002% ＜0.002%
Related substances(HPLC) individual impurity≤0.1% 0.03%
Total impurities≤0.3% ≤0.3%
Assay(non-aqueous titration) 97.5~102.5% 99.82%
关键字： 西力士；他达那非；Tadalafil ；Cialis；171596-29-5；Sildenafil ；西地那非
Zhuhai Jiayi Biotechnology Co, Ltd. Is a leading Chinese chemical supplier special in steroid peptides and related Pharmaceutical raw materials. Resort to its sophisticated technology, our company integrates R&D, producing, operating and marketing into an organic whole. Our company capital asserts is above 300 million RMB. According to the GMP standard, our company has built 30000 sq. M plant equipped the advanced equipment. The factory has a complete Q. A. & Q. C. System. We own several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and UV spectropho