Trametinib effects and side effects

Trametinib is in a class of medications called kinase inhibitors. It works by blocking the action of an abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.

Uses of Trametinib

Trametinib is used alone or with another medicine (dabrafenib) to treat a type of skin cancer (melanoma). It is also used with dabrafenib to treat thyroid cancer and a type of lung cancer (non-small cell lung cancer - NSCLC). Trametinib works by slowing the growth of cancer cells.

Side effects of Trametinib

Dizziness, diarrhea, nausea/vomiting, stomach pain, dry/itchy skin, acne, and dry mouth may occur after taking trametinib. If any of these effects persist or worsen, tell your doctor or pharmacist right away. To relieve dry mouth, suck on (sugar-free) hard candy or ice cubes, chew (sugar-free) gum, drink water, or use a saliva substitute.

Mouth and throat pain or sores may also occur. Brush your teeth carefully/gently, avoid alcohol-based mouthwashes, and rinse your mouth often with cold water mixed with baking soda or salt. It is best to eat soft, moist foods.

Precautions of Trametinib

Before taking trametinib, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients that may cause allergic reactions or other problems.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: high blood pressure, heart disease (heart failure), lung problems, bleeding/blood problems, diabetes, eye problems, stomach/intestine problems (such as diverticulitis).

This drug may make you dizzy or have blurred vision. Alcohol or marijuana (marijuana) can make you more dizzy. Do not drive, use machinery, or do anything that requires alertness or clear vision until you can do so safely. Limit alcoholic beverages. If you use marijuana (marijuana), talk to your doctor.

Older adults may be more sensitive to the side effects of this drug, especially swelling arms/legs and loss of appetite.