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ChemicalBook >> CAS DataBase List >> 9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one

9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one

9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one price.
  • $65 - $6254
  • Product name: 9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one
  • CAS: 1223001-51-1
  • MF: C24H15F3N4O
  • MW: 432.4
  • EINECS:
  • MDL Number:MFCD18782652
  • Synonyms:9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one;9-(6-AMino-pyridin-3-yl)-...;9-(6-AMino-pyridin-3-yl)-1-(3-trifluoroMethyl-phenyl)-1H-benzo[h][1,6]naphthyridin-2-one;Torin 2, Free Base, >99%;Benzo[h]-1,6-naphthyridin-2(1H)-one, 9-(6-amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-;9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one Torin 2;Torin 2 9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one;9-(6-AMINOPYRIDIN-3-YL)-1-[3-(TRIFLUOROMETHYL)PHENYL]BENZO[H][1,6]NAPHTHYRIDIN-2-ONE
Price31 Properties Safety Information Description
31 prices
Selected condition：
Brand
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 50
  • 250mg
  • 1g
  • ManufacturerApexBio Technology
  • Product numberB1640
  • Product descriptionTorin2
  • Packaging50mg
  • Price$314
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60269
  • Product descriptionTorin2
  • Packaging10mg
  • Price$248
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1834
  • Product descriptionTorin2 99%
  • Packaging25mg
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146132
  • Product descriptionTorin2 >98%
  • Packaging100mg
  • Price$838.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146132
  • Product descriptionTorin2 >98%
  • Packaging250mg
  • Price$1504.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146132
  • Product descriptionTorin2 >98%
  • Packaging1g
  • Price$2839
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT102223
  • Product descriptionTorin 2
  • Packaging10mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFT102223
  • Product descriptionTorin 2
  • Packaging50mg
  • Price$472.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14185
  • Product descriptionTorin 2 ≥98%
  • Packaging5mg
  • Price$86
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14185
  • Product descriptionTorin 2 ≥98%
  • Packaging10mg
  • Price$161
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number14185
  • Product descriptionTorin 2 ≥98%
  • Packaging25mg
  • Price$336
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0236
  • Product descriptionTorin2 99.93%
  • Packaging5mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0236
  • Product descriptionTorin2 99.93%
  • Packaging10mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0236
  • Product descriptionTorin2 99.93%
  • Packaging50mg
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0236
  • Product descriptionTorin2 99.93%
  • Packaging100mg
  • Price$490
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0236
  • Product descriptionTorin2 99.93%
  • Packaging200mg
  • Price$846
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology B1640 Torin2 50mg $314 2021-12-16 Buy
Arctom CFN60269 Torin2 10mg $248 2021-12-16 Buy
Axon Medchem Axon1834 Torin2 99% 25mg $330 2021-12-16 Buy
Biorbyt Ltd orb146132 Torin2 >98% 100mg $838.1 2021-12-16 Buy
Biorbyt Ltd orb146132 Torin2 >98% 250mg $1504.5 2021-12-16 Buy
Biorbyt Ltd orb146132 Torin2 >98% 1g $2839 2021-12-16 Buy
Biosynth Carbosynth FT102223 Torin 2 10mg $135 2021-12-16 Buy
Biosynth Carbosynth FT102223 Torin 2 50mg $472.5 2021-12-16 Buy
Cayman Chemical 14185 Torin 2 ≥98% 5mg $86 2024-03-01 Buy
Cayman Chemical 14185 Torin 2 ≥98% 10mg $161 2024-03-01 Buy
Cayman Chemical 14185 Torin 2 ≥98% 25mg $336 2024-03-01 Buy
ChemScene CS-0236 Torin2 99.93% 5mg $65 2021-12-16 Buy
ChemScene CS-0236 Torin2 99.93% 10mg $110 2021-12-16 Buy
ChemScene CS-0236 Torin2 99.93% 50mg $330 2021-12-16 Buy
ChemScene CS-0236 Torin2 99.93% 100mg $490 2021-12-16 Buy
ChemScene CS-0236 Torin2 99.93% 200mg $846 2021-12-16 Buy
Next Last

Properties

Melting point :>275° C (dec.)
Boiling point :623.7±55.0 °C(Predicted)
Density :1.427
storage temp. :2-8°C
solubility :Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form :powder
pka :5.66±0.26(Predicted)
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Torin 2 is a potent and selective mTOR inhibitor with IC50 of 0.25 nM in p53?/? MEFs cell line; 800-fold greater selectivity for mTOR than PI3K and improved pharmacokinetic properties. Inhibition of ATM/ATR/DNA-PK with EC50 of 28 nM/35 nM/118 nM,in PC3 cell lines respectively.

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Suppliers and manufacturers

career henan chemical co
9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one
$7.00 /1KG
9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one CAS:1223001-51-1
ATK CHEMICAL COMPANY LIMITED
Biochempartner
Hubei xin bonus chemical co. LTD
BOC Sciences
Chongqing Chemdad Co., Ltd
CONIER CHEM AND PHARMA LIMITED
Zhengzhou Alfa Chemical Co.,Ltd
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Dideu Industries Group Limited