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ChemicalBook >> CAS DataBase List >> (2R,5S)-5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-Oxathiolane-2-carboxylic acid, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester

(2R,5S)-5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-Oxathiolane-2-carboxylic acid, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester

(2R,5S)-5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-Oxathiolane-2-carboxylic acid, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester price.
  • $102 - $1275
  • Product name: (2R,5S)-5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-Oxathiolane-2-carboxylic acid, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
  • CAS: 764659-72-5
  • MF: C18H26FN3O4S
  • MW: 399.48
  • EINECS:1592732-453-0
  • MDL Number:MFCD09753268
  • Synonyms:(2R,5S)-(1R,2S,5R)-2-Isopropyl-5-Methylcyclohexyl 5-(4-aMino-5-fluoro-2-oxopyriMidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate;(2R,5S)-5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-Oxathiolane-2-carboxylic acid, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester;(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid;(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S;Emtricitabine impurity 9/Emtricitabine Menthyl Ester/(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester;[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl] 5-(4-amino-5-fluoro-2-oxopyrimidin-1-yl)-1,3-oxathiolane-2-carboxylate;(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid (1R,2S,5R)-5-;Emtricitabine Menthyl Ester Impurity
6 prices
Selected condition:
Brand
  • Alichem
  • Chemenu
  • Crysdot
  • Medical Isotopes, Inc.
  • TRC
Package
  • 1g
  • 25g
  • 100g
  • ManufacturerAlichem
  • Product number764659725
  • Product description(2R,5S)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate
  • Packaging100g
  • Price$288.4
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM166684
  • Product description(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylicacid(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexylester 95%
  • Packaging25g
  • Price$102
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM166684
  • Product description(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylicacid(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexylester 95%
  • Packaging100g
  • Price$262
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11060596
  • Product description(2R,5S)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate 95+%
  • Packaging100g
  • Price$277
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number53778
  • Product description(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylicAcid(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexylEster
  • Packaging1g
  • Price$1275
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberA609705
  • Product description(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylicAcid(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexylEster
  • Packaging1g
  • Price$945
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alichem 764659725 (2R,5S)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate 100g $288.4 2021-12-16 Buy
Chemenu CM166684 (2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylicacid(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexylester 95% 25g $102 2021-12-16 Buy
Chemenu CM166684 (2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylicacid(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexylester 95% 100g $262 2021-12-16 Buy
Crysdot CD11060596 (2R,5S)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate 95+% 100g $277 2021-12-16 Buy
Medical Isotopes, Inc. 53778 (2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylicAcid(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexylEster 1g $1275 2021-12-16 Buy
TRC A609705 (2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylicAcid(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexylEster 1g $945 2021-12-16 Buy

Properties

Melting point :190 - 192°C
Boiling point :508.5±60.0 °C(Predicted)
Density :1.47
storage temp. :Refrigerator
solubility :Chloroform (Slightly), DMSO (Sparingly, Heated), Methanol (Slightly, Sonicated)
pka :2.40±0.10(Predicted)
form :Solid
color :Off-White to Pale Brown

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(2R,5S)-5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-Oxathiolane-2-carboxylic acid, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester is an intermediate in the synthesis of Emtricitabine (E525000). A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).

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