AG 957
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- $37 - $230
- Product name: AG 957
- CAS: 140674-76-6
- MF: C15H15NO4
- MW: 273.28
- EINECS:
- MDL Number:MFCD01074970
- Synonyms:Lavendustin C Analog, Methyl-4-[N-(2μ,5μ-dihydroxybenzyl)amino]benzoate;NSC 654705;TYRPHOSTIN 957;TYRPHOSTIN AG 957;AG 957;4-AMINO-N-(2,5-DIHYDROXYBENZYL)METHYL BENZOATE;LAVENDUSTIN C ANALOG;METHYL-4-[N-(2',5'-DIHYDROXYBENZYL)AMINO]BENZOATE
8 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- TRC
Package
- 1MG
- 5mg
- 10mg
- ManufacturerAK Scientific
- Product number0242CA
- Product descriptionBenzoicacid,4-[[(2,5-dihydroxyphenyl)methyl]amino]-,methylester
- Packaging5mg
- Price$226
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000268
- Product descriptionAG 957 95.00%
- Packaging1MG
- Price$135.45
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5826
- Product descriptionAG957
- Packaging5mg
- Price$124
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC5826
- Product descriptionAG957
- Packaging10mg
- Price$230
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17259
- Product descriptionAG957 ≥95%
- Packaging1mg
- Price$37
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17259
- Product descriptionAG957 ≥95%
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17259
- Product descriptionAG957 ≥95%
- Packaging10mg
- Price$213
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberT947970
- Product descriptionTyrphostinAG957
- Packaging1mg
- Price$40
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 0242CA | Benzoicacid,4-[[(2,5-dihydroxyphenyl)methyl]amino]-,methylester | 5mg | $226 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000268 | AG 957 95.00% | 1MG | $135.45 | 2021-12-16 | Buy |
| ApexBio Technology | C5826 | AG957 | 5mg | $124 | 2021-12-16 | Buy |
| ApexBio Technology | C5826 | AG957 | 10mg | $230 | 2021-12-16 | Buy |
| Cayman Chemical | 17259 | AG957 ≥95% | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 17259 | AG957 ≥95% | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 17259 | AG957 ≥95% | 10mg | $213 | 2024-03-01 | Buy |
| TRC | T947970 | TyrphostinAG957 | 1mg | $40 | 2021-12-16 | Buy |
Properties
Boiling point :504.2±45.0 °C(Predicted)
Density :1.337±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: soluble
form :crystalline solid
pka :10.30±0.43(Predicted)
Density :1.337±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :DMSO: soluble
form :crystalline solid
pka :10.30±0.43(Predicted)
Safety Information
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Description
Tyrphostins are tyrosine phosphorylation inhibitors that act by inhibiting tyrosine kinases. AG957 is a tyrphostin that targets transforming Bcr-Abl fusion proteins (p185Bcr-Abl, p210Bcr-Abl), as well as normal c-Abl (IC50s = 4.3, 1, and 7.1 μM, respectively, for human proteins). It also inhibits epidermal growth factor receptor (IC50 = 0.25 μM). As the constitutively-active 210 kDa Bcr-Abl fusion protein commonly occurs in chronic myelogenous leukemia (CML) cells, AG957 is commonly used to study Bcr-Abl signaling in the CML K562 cell line. AG957 is also used to study signaling through c-Abl.Related product price
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