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ChemicalBook >> CAS DataBase List >> BIX 01294

BIX 01294

$125 - $1600
Product name: BIX 01294
CAS: 1392399-03-9
MF: C28H41Cl3N6O2
MW: 600.02314
EINECS:
MDL Number:MFCD16618384
Synonyms:BIX 01294 Trihydrochloride Hydrate;4-Quinazolinamine, 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-, hydrochloride (1:3);2-(Hexahydro-4-Methyl-1H-1,4-Diazepin-1-yl)-6,7-Dimethoxy-[1-(Phenylmethyl)-4-Piperidynyl]-4-Quinazolinamine Trihydrochloride BIX01294 hydrochloride;BIX01294 hydrochloride;BIX01294 3hydrochloride;Trihydrochloride Hydrate;N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine;BIX 01204

Price13 Properties Safety Information Description

13 prices

Selected condition：

Brand

Adipogen Life Sciences
AK Scientific
Arctom
Biosynth Carbosynth
Crysdot
DC Chemicals
Sigma-Aldrich
TCI Chemical
TRC

Package

002
5mg
003
250mg
001
10mg
20mg
25mg
50mg

ManufacturerAdipogen Life Sciences
Product numberAG-CR1-0150-M025
Product descriptionBIX01294.trihydrochloride ≥98%(NMR,HPLC)
Packaging25mg
Price$220
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number2272AH
Product description2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinaminetrihydrochloride
Packaging10mg
Price$146
Updated2021-12-16
Buy

ManufacturerArctom
Product numberCFN60292
Product descriptionBIX01294
Packaging20mg
Price$238
Updated2021-12-16
Buy

ManufacturerBiosynth Carbosynth
Product numberBB162787
Product descriptionBIX 01294
Packaging10mg
Price$125
Updated2021-12-16
Buy

ManufacturerBiosynth Carbosynth
Product numberBB162787
Product descriptionBIX 01294
Packaging50mg
Price$437.5
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD31003649
Product descriptionBIX01294trihydrochloride 95+%
Packaging25mg
Price$140
Updated2021-12-16
Buy

ManufacturerDC Chemicals
Product number020575
Product descriptionBIX01294Trihydrochloride
Packaging001
Price$400
Updated2021-12-16
Buy

ManufacturerDC Chemicals
Product number020575
Product descriptionBIX01294Trihydrochloride
Packaging002
Price$800
Updated2021-12-16
Buy

ManufacturerDC Chemicals
Product number020575
Product descriptionBIX01294Trihydrochloride
Packaging003
Price$1600
Updated2021-12-16
Buy

ManufacturerSigma-Aldrich
Product numberB9311
Product descriptionBIX 01294 trihydrochloride hydrate ≥98% (HPLC), powder
Packaging5mg
Price$221
Updated2024-03-01
Buy

ManufacturerSigma-Aldrich
Product numberB9311
Product descriptionBIX 01294 trihydrochloride hydrate ≥98% (HPLC), powder
Packaging25mg
Price$525
Updated2024-03-01
Buy

ManufacturerTCI Chemical
Product numberB4211
Product descriptionBIX 01294 Trihydrochloride Hydrate >85.0%(N)
Packaging25mg
Price$608
Updated2024-03-01
Buy

ManufacturerTRC
Product numberB591600
Product descriptionBIX01294Trihydrochloride
Packaging250mg
Price$1175
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Adipogen Life Sciences	AG-CR1-0150-M025	BIX01294.trihydrochloride ≥98%(NMR,HPLC)	25mg	$220	2021-12-16	Buy
AK Scientific	2272AH	2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinaminetrihydrochloride	10mg	$146	2021-12-16	Buy
Arctom	CFN60292	BIX01294	20mg	$238	2021-12-16	Buy
Biosynth Carbosynth	BB162787	BIX 01294	10mg	$125	2021-12-16	Buy
Biosynth Carbosynth	BB162787	BIX 01294	50mg	$437.5	2021-12-16	Buy
Crysdot	CD31003649	BIX01294trihydrochloride 95+%	25mg	$140	2021-12-16	Buy
DC Chemicals	020575	BIX01294Trihydrochloride	001	$400	2021-12-16	Buy
DC Chemicals	020575	BIX01294Trihydrochloride	002	$800	2021-12-16	Buy
DC Chemicals	020575	BIX01294Trihydrochloride	003	$1600	2021-12-16	Buy
Sigma-Aldrich	B9311	BIX 01294 trihydrochloride hydrate ≥98% (HPLC), powder	5mg	$221	2024-03-01	Buy
Sigma-Aldrich	B9311	BIX 01294 trihydrochloride hydrate ≥98% (HPLC), powder	25mg	$525	2024-03-01	Buy
TCI Chemical	B4211	BIX 01294 Trihydrochloride Hydrate >85.0%(N)	25mg	$608	2024-03-01	Buy
TRC	B591600	BIX01294Trihydrochloride	250mg	$1175	2021-12-16	Buy

Properties

storage temp. :Inert atmosphere,2-8°C
solubility :H2O: >20mg/mL
form :powder
color :white

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

BIX01294 hydrochloride inhibits G9a. The histone methyltransferase (HMTase) G9a can mono- or dimethylate lysine 9 on histone 3 (H3), contributing to early embryogenesis, genomic imprinting, and lymphocyte development. BIX01294 hydrochloride is a selective inhibitor of G9a HMTase (IC₅₀ = 1.7 μM). It less effectively inhibits the HMTase G9a-like protein (GLP; IC₅₀ = 38 μM) and has no effect on other known HMTases. BIX01294 hydrochloride has been used in combination with the calcium channel activator BayK8644 to facilitate the generation of induced pluripotent stem cells from somatic cells in vitro. BIX01294 hydrochloride is an inhibitor of HDAC.

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