Welcome to chemicalbook!
China English Japan Germany
400-158-6606
18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide
Structured search
Inquriy
Try our best to find the right business for you.
Messages
Do not miss inquiry messages Please log in to view all inquiry messages.
My chemicalbook My chemicalbook

Welcome back!

RFQ
skype
MY Account
Top
ChemicalBook >> CAS DataBase List >> GDC-0068

GDC-0068

GDC-0068 price.
  • $28 - $2864
  • Product name: GDC-0068
  • CAS: 1001264-89-6
  • MF: C24H32ClN5O2
  • MW: 458
  • EINECS:
  • MDL Number:MFCD22124514
  • Synonyms:(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone;Ipatasertib (GDC-0068);(S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one;(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone Ipatasertib (GDC-0068);GDC-0068 (2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone;(2S)-2-(4-Chlorophenyl)-1-{4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]-1-piperazinyl}-3-(isopropylamino)-1-propanone;Ipatasertib (GDC-0068,RG 7440);GDC-0068;RG7440; GDC0068; GDC 0068; RG-7440; RG 7440
Price37 Properties Safety Information Description
37 prices
Selected condition：
Brand
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
Package
  • 1mg
  • 1unit
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 10mM(in 1mL DMSO)
  • 250mg
  • 500mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberSYN5726
  • Product descriptionGDC-0068
  • Packaging50mg
  • Price$757
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ67082
  • Product descriptionGDC-0068, 98%
  • Packaging5mg
  • Price$241
  • Updated2023-06-20
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0013721
  • Product descriptionGDC-0068 95.00%
  • Packaging5MG
  • Price$459.8
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3006
  • Product descriptionGDC-0068(RG7440)
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3006
  • Product descriptionGDC-0068(RG7440)
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3006
  • Product descriptionGDC-0068(RG7440)
  • Packaging10mM(in 1mL DMSO)
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3006
  • Product descriptionGDC-0068(RG7440)
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3006
  • Product descriptionGDC-0068(RG7440)
  • Packaging50mg
  • Price$520
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3006
  • Product descriptionGDC-0068(RG7440)
  • Packaging100mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60068
  • Product descriptionIpatasertib(GDC-0068) ≥98%
  • Packaging10mg
  • Price$208
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146127
  • Product descriptionIpatasertib (GDC-0068) >98%
  • Packaging100mg
  • Price$690.2
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146127
  • Product descriptionIpatasertib (GDC-0068) >98%
  • Packaging250mg
  • Price$1356.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb146127
  • Product descriptionIpatasertib (GDC-0068) >98%
  • Packaging1g
  • Price$2691.1
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC43222
  • Product descriptionIpatasertib
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC43222
  • Product descriptionIpatasertib
  • Packaging10mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC43222
  • Product descriptionIpatasertib
  • Packaging25mg
  • Price$187.5
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific SYN5726 GDC-0068 50mg $757 2021-12-16 Buy
Alfa Aesar J67082 GDC-0068, 98% 5mg $241 2023-06-20 Buy
American Custom Chemicals Corporation API0013721 GDC-0068 95.00% 5MG $459.8 2021-12-16 Buy
ApexBio Technology A3006 GDC-0068(RG7440) 1unit $28 2021-12-16 Buy
ApexBio Technology A3006 GDC-0068(RG7440) 5mg $100 2021-12-16 Buy
ApexBio Technology A3006 GDC-0068(RG7440) 10mM(in 1mL DMSO) $100 2021-12-16 Buy
ApexBio Technology A3006 GDC-0068(RG7440) 10mg $150 2021-12-16 Buy
ApexBio Technology A3006 GDC-0068(RG7440) 50mg $520 2021-12-16 Buy
ApexBio Technology A3006 GDC-0068(RG7440) 100mg $650 2021-12-16 Buy
Arctom CFN60068 Ipatasertib(GDC-0068) ≥98% 10mg $208 2021-12-16 Buy
Biorbyt Ltd orb146127 Ipatasertib (GDC-0068) >98% 100mg $690.2 2021-12-16 Buy
Biorbyt Ltd orb146127 Ipatasertib (GDC-0068) >98% 250mg $1356.6 2021-12-16 Buy
Biorbyt Ltd orb146127 Ipatasertib (GDC-0068) >98% 1g $2691.1 2021-12-16 Buy
Biosynth Carbosynth FC43222 Ipatasertib 5mg $60 2021-12-16 Buy
Biosynth Carbosynth FC43222 Ipatasertib 10mg $100 2021-12-16 Buy
Biosynth Carbosynth FC43222 Ipatasertib 25mg $187.5 2021-12-16 Buy
Next Last

Properties

Melting point :>106°C (dec.)
Boiling point :669.4±55.0 °C(Predicted)
Density :1.254
storage temp. :Hygroscopic, Refrigerator, under inert atmosphere
solubility :Soluble in DMSO.
pka :13.11±0.40(Predicted)
form :Solid
color :peachy

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

GDC-0068 is a selective, ATP-competitive, pan-Akt inhibitor that targets Akt1, 2, and 3 with IC50 values of 5, 18, and 8 nM, respectively in cell-free assays. It is 620-fold selective for Akt over protein kinase A and has been shown to block Akt signaling selectively in cultured tumor cell lines characterized by activated Akt, halting cell cycle progression and reducing cell viability. In multiple tumor xenograft models, oral administration of GDC-0068 at 100 mg/kg/day can lead to delayed tumor growth and regression.

More related product prices

Rapamycin AZD5363 Pictilisib (GDC-0941) 1217486-61-7 MK-2206 2HCl 937174-76-0 Cenicriviroc

Related product price

Suppliers and manufacturers

career henan chemical co
GDC-0068
$2.00 /1kg
GDC-0068 CAS:1001264-89-6
ATK CHEMICAL COMPANY LIMITED
Biochempartner
Hubei Jusheng Technology Co.,Ltd.
BOC Sciences
Chongqing Chemdad Co., Ltd
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Shanghai UCHEM Inc.
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited