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ChemicalBook >> CAS DataBase List >> Lometrexol

Lometrexol

Lometrexol price.
  • $97 - $1395
  • Product name: Lometrexol
  • CAS: 106400-81-1
  • MF: C21H25N5O6
  • MW: 443.45
  • EINECS:
  • MDL Number:
  • Synonyms:Lometrexol;(6R)-5,10-Dideaza-5,6,7,8-tetrahydrofolic acid;N-[4-[2-[[(6R)-2-Amino-3,4,5,6,7,8-hexahydro-4-oxopyrido[2,3-d]pyrimidin]-6-yl]ethyl]benzoyl]-L-glutamic acid;N-[4-[2-[[(R)-2-Amino-4-oxo-1,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin]-6-yl]ethyl]benzoyl]-L-glutamic acid;L-Glutamic acid, N-(4-(2-((6R)-2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-D)pyrimidin-6-yl)ethyl)benzoyl)-;L-Glutamic acid, N-(4-(2-(2-amino-1,4,5,6,7,8-hexahydro-4-oxopyrido(2,3-D)pyrimidin-6-yl)ethyl)benzoyl)-, (R)-;Lometrexolum;Lometrexolum [inn-latin]
Price11 Properties Safety Information Description
11 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • ChemScene
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
Package
  • 1mg
  • 5MG
  • 10mg
  • 25mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0027262
  • Product descriptionLOMETREXOL HYDRATE 95.00%
  • Packaging5MG
  • Price$500.35
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18049
  • Product descriptionLometrexol ≥98%
  • Packaging1mg
  • Price$97
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18049
  • Product descriptionLometrexol ≥98%
  • Packaging5mg
  • Price$243
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0003423
  • Product descriptionLometrexol
  • Packaging1mg
  • Price$275
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0003423
  • Product descriptionLometrexol
  • Packaging5mg
  • Price$830
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0108147
  • Product descriptionLometrexol hydrate 99.20%
  • Packaging5mg
  • Price$830
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0108147
  • Product descriptionLometrexol hydrate 99.20%
  • Packaging10mg
  • Price$1395
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0003423
  • Product descriptionLometrexol
  • Packaging10mg
  • Price$1395
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number27666
  • Product descriptionLometrexol hydrate >95%
  • Packaging1mg
  • Price$990
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0040
  • Product descriptionLometrexol hydrate ≥95% (HPLC)
  • Packaging5mg
  • Price$254
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0040
  • Product descriptionLometrexol hydrate ≥95% (HPLC)
  • Packaging25mg
  • Price$666
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0027262 LOMETREXOL HYDRATE 95.00% 5MG $500.35 2021-12-16 Buy
Cayman Chemical 18049 Lometrexol ≥98% 1mg $97 2024-03-01 Buy
Cayman Chemical 18049 Lometrexol ≥98% 5mg $243 2024-03-01 Buy
ChemScene CS-0003423 Lometrexol 1mg $275 2021-12-16 Buy
ChemScene CS-0003423 Lometrexol 5mg $830 2021-12-16 Buy
ChemScene CS-0108147 Lometrexol hydrate 99.20% 5mg $830 2021-12-16 Buy
ChemScene CS-0108147 Lometrexol hydrate 99.20% 10mg $1395 2021-12-16 Buy
ChemScene CS-0003423 Lometrexol 10mg $1395 2021-12-16 Buy
Medical Isotopes, Inc. 27666 Lometrexol hydrate >95% 1mg $990 2021-12-16 Buy
Sigma-Aldrich SML0040 Lometrexol hydrate ≥95% (HPLC) 5mg $254 2024-03-01 Buy
Sigma-Aldrich SML0040 Lometrexol hydrate ≥95% (HPLC) 25mg $666 2024-03-01 Buy

Properties

Density :1.56±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: ≥5mg/mL
pka :3.60±0.10(Predicted)
form :powder
color :white to light yellow
Stability :Hygroscopic

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

Glycinamide ribonucleotide formyltransferase (GART) is a folate-dependent enzyme required for de novo purine synthesis. Lometrexol is a folate analog antimetabolite with antineoplastic activity. At nanomolar conentrations, it inhibits GART preventing de novo purine synthesis, inhibiting DNA synthesis, arresting cells in the S phase of the cell cycle, and inhibiting tumor cell proliferation.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
Aladdin Scientific J & K SCIENTIFIC LTD. LGM Pharma Chemsky (shanghai) International Co.,Ltd Sigma-Aldrich Beijing Jin Ming Biotechnology Co., Ltd. Shenzhen Polymeri Biochemical Technology Co., Ltd. DC Chemicals ChemeGen(Shanghai) Biotechnology Co.,Ltd.