M348
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- $32 - $870
- Product name: M348
- CAS: 899713-86-1
- MF: C18H17ClF3N3O3
- MW: 415.79
- EINECS:809-791-4
- MDL Number:MFCD05123530
- Synonyms:M348;ML348;N-[2-Chloro-5-(trifluoromethyl)phenyl]-4-(2-furanylcarbonyl)-1-piperazineacetamide;CS-2370;ML-348 (ML348);GNF-Pf-1127;ML 348;GNF-PF-1127;1-Piperazineacetamide, N-[2-chloro-5-(trifluoromethyl)phenyl]-4-(2-furanylcarbonyl)-
21 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Axon Medchem
- Cayman Chemical
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10
- 1mg
- 50
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- ManufacturerAK Scientific
- Product number0351CK
- Product descriptionN-[2-Chloro-5-(trifluoromethyl)phenyl]-2-[4-(2-furoyl)piperazin-1-yl]acetamide
- Packaging1mg
- Price$145
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4933
- Product descriptionML348
- Packaging50mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2646
- Product descriptionML348 99%
- Packaging10mg
- Price$104.5
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18523
- Product descriptionML348 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18523
- Product descriptionML348 ≥98%
- Packaging5mg
- Price$100
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18523
- Product descriptionML348 ≥98%
- Packaging10mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18523
- Product descriptionML348 ≥98%
- Packaging25mg
- Price$343
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5993
- Product descriptionML348 99.88%
- Packaging5mg
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5993
- Product descriptionML348 99.88%
- Packaging10mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5993
- Product descriptionML348 99.88%
- Packaging25mg
- Price$264
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5993
- Product descriptionML348 99.88%
- Packaging50mg
- Price$456
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5993
- Product descriptionML348 99.88%
- Packaging100mg
- Price$804
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9874
- Product descriptionML-348(ML348) >98%
- Packaging100mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC9874
- Product descriptionML-348(ML348) >98%
- Packaging250mg
- Price$850
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1901
- Product descriptionML348 ≥98% (HPLC)
- Packaging5MG
- Price$105
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1901
- Product descriptionML348 ≥98% (HPLC)
- Packaging25MG
- Price$424
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 0351CK | N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-[4-(2-furoyl)piperazin-1-yl]acetamide | 1mg | $145 | 2021-12-16 | Buy |
| ApexBio Technology | B4933 | ML348 | 50mg | $360 | 2021-12-16 | Buy |
| Axon Medchem | Axon2646 | ML348 99% | 10mg | $104.5 | 2021-12-16 | Buy |
| Cayman Chemical | 18523 | ML348 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 18523 | ML348 ≥98% | 5mg | $100 | 2024-03-01 | Buy |
| Cayman Chemical | 18523 | ML348 ≥98% | 10mg | $184 | 2024-03-01 | Buy |
| Cayman Chemical | 18523 | ML348 ≥98% | 25mg | $343 | 2024-03-01 | Buy |
| ChemScene | CS-5993 | ML348 99.88% | 5mg | $72 | 2021-12-16 | Buy |
| ChemScene | CS-5993 | ML348 99.88% | 10mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-5993 | ML348 99.88% | 25mg | $264 | 2021-12-16 | Buy |
| ChemScene | CS-5993 | ML348 99.88% | 50mg | $456 | 2021-12-16 | Buy |
| ChemScene | CS-5993 | ML348 99.88% | 100mg | $804 | 2021-12-16 | Buy |
| DC Chemicals | DC9874 | ML-348(ML348) >98% | 100mg | $500 | 2021-12-16 | Buy |
| DC Chemicals | DC9874 | ML-348(ML348) >98% | 250mg | $850 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML1901 | ML348 ≥98% (HPLC) | 5MG | $105 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1901 | ML348 ≥98% (HPLC) | 25MG | $424 | 2024-03-01 | Buy |
Properties
Boiling point :546.2±50.0 °C(Predicted)
Density :1.422±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : 25 mg/mL (60.13 mM; Need ultrasonic)
form :Powder
pka :13.13±0.70(Predicted)
Density :1.422±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMSO : 25 mg/mL (60.13 mM; Need ultrasonic)
form :Powder
pka :13.13±0.70(Predicted)
Safety Information
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| Signal word: | Danger | ||||||||||||||||
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Description
Lysophospholipase 1 (LYPLA1) is a protein palmitoyl thioesterase responsible for depalmitoylation of the oncogene HRas. Palmitoylation of such oncogenes is thought to be required for trafficking and malignant transformation, making LYPLA1 a target for downregulating oncogenic signaling. ML348 is a reversible LYPLA1 inhibitor with an IC50 value of 210 nM. It is 14-fold selective for LYPLA1 over LYPLA2 (IC50 = >3,000) and demonstrates little activity against a panel of more than 20 other serine hydrolases (IC50s = >10,000).More related product prices
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